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Charles River Introduces the First Rapid Animal-Free Bacterial Endotoxin Test
Endosafe® Trillium™ recombinant cascade reagent (rCR) cartridges provide an alternative option to bolster commitments to sustainability and animal welfare
Designed to deliver rapid, quantitative results, the rCR cartridges are pre-loaded with all the reagents required to perform an endotoxin test, eliminating need for preparation of multiple reagents, and reducing the opportunity for technician error. Additionally, the product is fully aligned and integrated with Charles River’s existing suite of Endosafe cartridge instrumentation and software, allowing for current limulus amebocyte lysate (LAL) cartridge clients to transition seamlessly.
Historically, endotoxin testing has relied on the
Charles River continues to apply the highest scientific standards when offering new and innovative products in its
“The launch of Charles River’s Endosafe® Trillium™ cartridge revolutionizes the way the industry approaches endotoxin testing while strengthening our united commitment to sustainability initiatives. This year, as we celebrate the 20th anniversary of the original Endosafe LAL reagent cartridge technology, we are excited to bring a new animal-free option to clients that leverages innovative technology, while continuing to offer our LAL-based offerings for clients whose work requires them.” –
Birgit Girshick, Corporate Executive Vice President & Chief Operating Officer, Charles River.
“We are proud to support our clients’ wide range of
BETneeds with this first-ever animal-free cartridge. In conjunction with our LAL-based cartridges, which utilize 95% less horseshoe crab raw material required for a traditional bacterial endotoxin test, the Trillium cartridge builds on our portfolio to provide our clients with robust animal-free and animal-reduced offerings.” – Gregory Marshall, Vice President and General Manager, Microbial Solutions, Charles River.
“Using the Endosafe® Trillium™ rCR cartridges alongside our routine testing was straightforward for our technicians, as the test method remains identical, and the results are reported the same way. We were pleased with the technology implementation, quality of data, and onboarding as it was simple and seamless, which is ideal when introducing such an impactful change in the microbiology lab. We look forward to moving to Endosafe® Trillium™ rCR cartridges for routine testing later in the year as part of our environmental sustainability efforts.” –
Greg White, Microbiology Laboratory Supervisor & Blackpool STEM Lead, DePuy Synthes International.
About Charles River
Charles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development, and safe manufacture of new therapies for the patients who need them. To learn more about our unique portfolio and breadth of services, visit www.criver.com.
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