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Charles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them.

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Charles River Laboratories Becomes Deltagen's Exclusive, Worldwide Custodian, Supplier of Knockout Mice Repository

WILMINGTON, Mass.--(BUSINESS WIRE)--Jan. 9, 2006--Charles River Laboratories International, Inc. (NYSE: CRL) (Charles River), a premier global provider of solutions that advance the drug discovery and development process, announces that it has established a worldwide collaboration with Deltagen, Inc., a leading provider of drug discovery tools. Deltagen has created one of the world's foremost repositories of knockout mice, and Charles River is pleased to become the sole source provider of these repository materials, including cryopreserved mouse embryos, sperm and ES cells. This collaboration further strengthens the long-term relationship that Charles River and Deltagen have enjoyed and allows the research community easy access to all of Deltagen's knockout mouse lines in all forms from ES cells to live animals.

William Barbo, Charles River Laboratories Corporate Vice President, Research Model Services, said, "Charles River is delighted about entering into this long-term services agreement with Deltagen. This collaboration allows the customers of both companies to enjoy unsurpassed access to Deltagen's exciting mouse models, as well as Charles River's worldwide breeding, genotyping and phenotyping services."

Robert J. Driscoll, Ph.D., J.D., CEO of Deltagen, added, "Deltagen is pleased to place our repository with a market leader like Charles River. By having all of our knockout mouse lines under one roof, we can better market and distribute our product line. By partnering with Charles River and their experienced world wide Transgenic and Research Model Services group, our customers will enjoy fast and consistent delivery of the targets important to them."

About Charles River Laboratories

Charles River Laboratories, based in Wilmington, Massachusetts, U.S., is a global provider of solutions that advance the drug discovery and development process. Our leading-edge products and services are designed to enable our clients to bring drugs to market faster and more efficiently. Backed by our rigorous, best-in-class procedures and our proven data collection, analysis and reporting capabilities, our products and services are organized into three categories spanning every step of the drug development pipeline: Research Models and Services, Preclinical Services, and Clinical Services. Charles River's customer base includes all of the major pharmaceutical companies and many biotechnology companies, government agencies and leading hospitals and academic institutions. Charles River's 8,400 employees serve clients in more than 50 countries. For more information on Charles River, visit our website at www.criver.com.

About Deltagen

Deltagen, Inc., based in San Carlos, California, U.S., is a leading provider of drug discovery tools to the biopharmaceutical industry. Deltagen offers access to its extensive inventory of knockout mouse lines and related phenotypic data, which enhance the efficiency of target validation and drug discovery. In addition, Deltagen offers target validation data in the areas of immunology and metabolic diseases. Deltagen's products and programs have been validated by customers and partners such as Eli Lilly & Co., GlaxoSmithKline, Merck & Co. and Pfizer Inc. For more information on Deltagen, visit www.deltagen.com.

CONTACT: Charles River Laboratories
Elizabeth Ferber
Director, Global Communications
T: 978-658-6000 ext. 1693
F: 978-658-7841
corpcomm@crl.com

SOURCE: Charles River Laboratories

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