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Document and Entity Information - shares	9 Months Ended
Document and Entity Information - shares	Sep. 30, 2017	Oct. 27, 2017
Document and Entity Information [Abstract]
Entity Registrant Name	CHARLES RIVER LABORATORIES INTERNATIONAL INC
Entity Central Index Key	0001100682
Current Fiscal Year End Date	--12-30
Entity Filer Category	Large Accelerated Filer
Document Type	10-Q
Document Period End Date	Sep. 30, 2017
Document Fiscal Year Focus	2017
Document Fiscal Period Focus	Q3
Amendment Flag	false
Entity Common Stock, Shares Outstanding		47,361,523

CONDENSED CONSOLIDATED STATEMENTS OF INCOME (UNAUDITED) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Income Statement [Abstract]
Service revenue	$ 326,711	$ 292,849	$ 960,640	$ 806,397
Product revenue	137,521	132,871	418,484	408,246
Total revenue	464,232	425,720	1,379,124	1,214,643
Costs and expenses:
Cost of services provided (excluding amortization of intangible assets)	219,368	200,118	640,904	543,588
Cost of products sold (excluding amortization of intangible assets)	67,660	69,332	203,655	204,270
Selling, general and administrative	92,863	85,650	278,886	269,067
Amortization of intangible assets	10,357	11,825	30,913	29,390
Operating income	73,984	58,795	224,766	168,328
Other income (expense):
Interest income	134	523	497	1,008
Interest expense	(7,667)	(7,079)	(22,053)	(20,199)
Other income, net	6,488	1,017	24,692	10,059
Income from continuing operations, before income taxes	72,939	53,256	227,902	159,196
Provision for income taxes	19,945	15,565	73,272	48,385
Income from continuing operations, net of income taxes	52,994	37,691	154,630	110,811
Income (loss) from discontinued operations, net of income taxes	(39)	342	(114)	328
Net income	52,955	38,033	154,516	111,139
Less: Net income attributable to noncontrolling interests	481	298	1,312	1,054
Net income attributable to common shareholders	$ 52,474	$ 37,735	$ 153,204	$ 110,085
Basic:
Continuing operations attributable to common shareholders (in dollars per share)	$ 1.11	$ 0.79	$ 3.23	$ 2.34
Discontinued operations (in dollars per share)	0.00	0.01	0.00	0.00
Net income attributable to common shareholders (in dollars per share)	1.11	0.80	3.22	2.34
Diluted:
Continuing operations attributable to common shareholders (in dollars per share)	1.09	0.78	3.17	2.29
Discontinued operations (in dollars per share)	0.00	0.01	0.00	0.01
Net income attributable to common shareholders (in dollars per share)	$ 1.08	$ 0.79	$ 3.16	$ 2.30

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (UNAUDITED) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Statement of Comprehensive Income [Abstract]
Net income	$ 52,955	$ 38,033	$ 154,516	$ 111,139
Other comprehensive income (loss):
Foreign currency translation adjustment and other	24,570	(16,888)	69,242	(32,798)
Amortization of net loss and prior service benefit included in net periodic cost for pension and other post-retirement benefit plans	883	1,176	2,638	1,961
Comprehensive income, before income taxes	78,408	22,321	226,396	80,302
Income tax expense related to items of other comprehensive income (Note 9)	153	140	776	424
Comprehensive income, net of income taxes	78,255	22,181	225,620	79,878
Less: Comprehensive income (loss) related to noncontrolling interests, net of income taxes	766	0	1,964	(9)
Comprehensive income attributable to common shareholders, net of income taxes	$ 77,489	$ 22,181	$ 223,656	$ 79,887

CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED) - USD ($) $ in Thousands	Sep. 30, 2017	Dec. 31, 2016
Current assets:
Cash and cash equivalents	$ 123,618	$ 117,626
Trade receivables, net	422,335	364,050
Inventories	107,372	95,833
Prepaid assets	42,695	34,315
Other current assets	86,358	45,008
Total current assets	782,378	656,832
Property, plant and equipment, net	767,192	755,827
Goodwill	800,247	787,517
Client relationships and Other intangible assets, net	375,447	394,448
Deferred tax assets	30,856	28,746
Other assets	109,798	88,430
Total assets	2,865,918	2,711,800
Current liabilities:
Current portion of long-term debt and capital leases	27,090	27,313
Accounts payable	66,232	68,485
Accrued compensation	86,402	93,471
Deferred revenue	108,984	127,731
Accrued liabilities	91,783	84,470
Other current liabilities	33,614	26,500
Current liabilities of discontinued operations	1,650	1,623
Total current liabilities	415,755	429,593
Long-term debt, net and capital leases	1,155,998	1,207,696
Deferred tax liabilities	81,783	55,717
Other long-term liabilities	167,493	159,239
Long-term liabilities of discontinued operations	4,395	5,771
Total liabilities	1,825,424	1,858,016
Commitments and contingencies (Note 13)
Redeemable noncontrolling interest	15,785	14,659
Equity:
Preferred stock, $0.01 par value; 20,000 shares authorized; no shares issued and outstanding	0	0
Common stock, $0.01 par value; 120,000 shares authorized; 87,417 shares issued and 47,324 shares outstanding as of September 30, 2017, and 86,301 shares issued and 47,363 shares outstanding as of December 31, 2016	874	863
Additional paid-in capital	2,545,351	2,477,371
Retained earnings	318,507	165,303
Treasury stock, at cost 40,093 shares and 38,938 shares as of September 30, 2017, and December 31, 2016, respectively	(1,659,907)	(1,553,005)
Accumulated other comprehensive loss	(183,312)	(253,764)
Total equity attributable to common shareholders	1,021,513	836,768
Noncontrolling interests	3,196	2,357
Total equity	1,024,709	839,125
Total liabilities, redeemable noncontrolling interest and equity	2,865,918	2,711,800
Client relationships, net
Current assets:
Client relationships and Other intangible assets, net	304,382	320,157
Other intangible assets, net
Current assets:
Client relationships and Other intangible assets, net	$ 71,065	$ 74,291

CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED) (Parenthetical) - $ / shares	Sep. 30, 2017	Dec. 31, 2016
Statement of Financial Position [Abstract]
Preferred stock, par value (in dollars per share)	$ 0.01	$ 0.01
Preferred stock, shares authorized (in shares)	20,000,000	20,000,000
Preferred stock, shares issued (in shares)	0	0
Preferred stock, shares outstanding (in shares)	0	0
Common stock, par value (in dollars per share)	$ 0.01	$ 0.01
Common stock, shares authorized (in shares)	120,000,000	120,000,000
Common stock, shares issued (in shares)	87,417,000	86,301,000
Common stock, shares outstanding (in shares)	47,324,000	47,363,000
Treasury stock (in shares)	40,093,000	38,938,000

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016
Cash flows relating to operating activities
Net income	$ 154,516	$ 111,139
Income (loss) from discontinued operations, net of income taxes	(114)	328
Income from continuing operations, net of income taxes	154,630	110,811
Adjustments to reconcile net income from continuing operations to net cash provided by operating activities:
Depreciation and amortization	97,675	91,116
Stock-based compensation	32,902	32,647
Deferred income taxes	18,176	(270)
Gain on divestiture	(10,577)	0
Other, net	(3,579)	92
Changes in assets and liabilities:
Trade receivables, net	(42,712)	(43,260)
Inventories	(9,500)	(4,352)
Accounts payable	(6,160)	17,184
Accrued compensation	(10,548)	8,163
Other assets and liabilities, net	(26,469)	(13,879)
Net cash provided by operating activities	193,838	198,252
Cash flows relating to investing activities
Acquisition of businesses and assets, net of cash acquired	(22,474)	(597,607)
Capital expenditures	(53,928)	(29,609)
Purchases of investments	(42,135)	(20,278)
Proceeds from sale of investments and distributions from venture capital investments	6,604	26,035
Proceeds from divestiture	72,462	0
Other, net	(288)	3,790
Net cash used in investing activities	(39,759)	(617,669)
Cash flows relating to financing activities
Proceeds from long-term debt and revolving credit facility	229,255	926,781
Proceeds from exercises of stock options	35,089	21,643
Payments on long-term debt, revolving credit facility and capital lease obligations	(309,258)	(526,983)
Purchase of treasury stock	(106,902)	(12,226)
Other, net	(3,650)	(4,533)
Net cash (used in) provided by financing activities	(155,466)	404,682
Discontinued operations
Net cash used in operating activities from discontinued operations	(1,489)	(1,434)
Effect of exchange rate changes on cash, cash equivalents, and restricted cash	9,135	4,325
Net change in cash, cash equivalents, and restricted cash	6,259	(11,844)
Cash, cash equivalents, and restricted cash, beginning of period	119,894	119,963
Cash, cash equivalents, and restricted cash, end of period	126,153	108,119
Supplemental cash flow information:
Cash, cash equivalents, and restricted cash, end of period	$ 119,894	$ 119,963

Basis of Presentation	9 Months Ended
Basis of Presentation	Sep. 30, 2017
Organization, Consolidation and Presentation of Financial Statements [Abstract]
BASIS OF PRESENTATION	BASIS OF PRESENTATION The accompanying condensed consolidated financial statements are unaudited and have been prepared by Charles River Laboratories International, Inc. (the Company) in accordance with accounting principles generally accepted in the United States (U.S. GAAP) and pursuant to the rules and regulations of the Securities and Exchange Commission. The year-end condensed consolidated balance sheet data was derived from the Company’s audited consolidated financial statements, but does not include all disclosures required by U.S. GAAP. These unaudited condensed consolidated financial statements should be read in conjunction with the Company’s Annual Report on Form 10-K for fiscal year 2016. The unaudited condensed consolidated financial statements, in the opinion of management, reflect all normal and recurring adjustments necessary for a fair statement of the Company’s financial position and results of operations. The Company has reclassified certain amounts in the unaudited condensed consolidated statements of cash flows for prior periods to conform to the current year presentation. See “Newly Adopted Accounting Pronouncements” below. Use of Estimates The preparation of unaudited condensed consolidated financial statements in accordance with U.S. GAAP requires that the Company make estimates and judgments that may affect the reported amounts of assets, liabilities, redeemable noncontrolling interest, revenues, expenses and related disclosure of contingent assets and liabilities. On an on-going basis, the Company evaluates its estimates, judgments, and methodologies. The Company bases its estimates on historical experience and on various other assumptions that are believed to be reasonable, the results of which form the basis for making judgments about the carrying values of assets and liabilities. Actual results may differ from these estimates under different assumptions or conditions. Changes in estimates are reflected in reported results in the period in which they become known. Consolidation The Company’s unaudited condensed consolidated financial statements reflect its financial statements and those of its subsidiaries in which the Company holds a controlling financial interest. For consolidated entities in which the Company owns or is exposed to less than 100% of the economics, the Company records net income (loss) attributable to noncontrolling interests in its consolidated statements of income equal to the percentage of the economic or ownership interest retained in such entities by the respective noncontrolling parties. Intercompany balances and transactions are eliminated in consolidation. The Company’s fiscal year is typically based on a 52-week year, with each quarter composed of 13 weeks ending on the last Saturday on, or closest to, March 31, June 30, September 30, and December 31. A 53^rd week was included in the fourth quarter of fiscal year 2016, which is occasionally necessary to align with a December 31 calendar year end. Summary of Significant Accounting Policies The Company’s significant accounting policies are described in Note 1, “Description of Business and Summary of Significant Accounting Policies,” in the Company’s Annual Report on Form 10-K for fiscal year 2016. Newly Adopted Accounting Pronouncements In November 2016, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) 2016-18, “Restricted Cash.” The standard addresses the classification and presentation of restricted cash and restricted cash equivalents within the statement of cash flows. The Company elected to early adopt this standard in fiscal year 2017 and applied the changes retrospectively to all prior periods presented in its unaudited condensed consolidated statements of cash flows. The Company historically excluded restricted cash balances, recorded in current and long-term other assets, from cash and cash equivalents within the unaudited condensed consolidated statements of cash flows, reflecting transfers between cash, cash equivalents, and restricted cash as a cash flow classified within cash flows relating to operating activities. As a result of the adoption of this standard, the Company combined restricted cash balances of $2.4 million and $2.0 million as of September 24, 2016, and December 26, 2015, respectively, with cash and cash equivalents when reconciling the beginning and ending balances within the unaudited condensed consolidated statements of cash flows for the nine months ended September 24, 2016. In August 2016, the FASB issued ASU 2016-15, “Classification of Certain Cash Receipts and Cash Payments.” The standard addresses the classification of certain transactions within the statement of cash flows, including cash payments for debt prepayment or debt extinguishment costs, contingent consideration payments made after a business combination, and distributions received from equity method investments. The Company elected to early adopt this standard in fiscal year 2017 and applied the changes retrospectively to all prior periods presented within its unaudited condensed consolidated statements of cash flows. As a result of the adoption of this standard, the Company reclassified $2.2 million from investing activities to operating activities within the unaudited condensed consolidated statements of cash flows for the nine months ended September 24, 2016. In March 2016, the FASB issued ASU 2016-09, “Improvements to Employee Share-Based Payment Accounting.” The standard reduces complexity in several aspects of the accounting for employee share-based compensation, including the income tax consequences, classification of awards as either equity or liabilities, and classification within the statement of cash flows. The Company adopted this standard in fiscal year 2017, and applied the changes as required by each amendment to its unaudited condensed consolidated financial statements and related disclosures. Under ASU 2016-09, the Company adopted the amendment to recognize excess tax benefits and tax deficiencies in the consolidated statements of income on a prospective basis, to present excess tax benefits within operating activities within the unaudited condensed consolidated statements of cash flows on a retrospective basis, and elected to change its accounting policy to account for forfeitures as they occur on a modified retrospective basis. The adoption to recognize excess tax benefits and tax deficiencies within the unaudited condensed consolidated statements of income on a prospective basis could result in fluctuations in the effective tax rate period-over-period, depending on how many awards vest and the volatility of the Company’s stock price. During the three months ended September 30, 2017, the impact to the provision for income taxes within the unaudited condensed consolidated statements of income was an excess tax benefit of $0.9 million. During the nine months ended September 30, 2017, the impact on the provision for income taxes within the unaudited condensed consolidated statements of income was an excess tax benefit of $9.7 million. Further, for the three and nine months ended September 30, 2017, the Company excluded the effect of windfall tax benefits from the hypothetical proceeds used to calculate the repurchase of shares under the treasury stock method for the calculation of diluted earnings per share. The adoption of the amendment to present excess tax benefits within operating activities within the unaudited condensed consolidated statements of cash flows on a retrospective basis resulted in the reclassification of a cash inflow of $9.5 million from cash provided by financing activities to cash provided by operating activities for the nine months ended September 24, 2016. The Company had previously classified cash paid for tax withholding purposes as a financing activity within the unaudited condensed consolidated statements of cash flows; therefore, there was no change related to this requirement under the amendment. The Company’s election to change its accounting policy to account for forfeitures when they occur on a modified retrospective basis resulted in an immaterial impact on its unaudited condensed consolidated financial statements and related disclosures. Newly Issued Accounting Pronouncements In August 2017, the FASB issued ASU 2017-12, “Derivatives and Hedging (Topic 815) Targeted Improvements to Accounting for Hedging Activities.” ASU 2017-12 refines and expands hedge accounting for both financial and commodity risks. It also creates more transparency around how economic results are presented, both on the face of the financial statements and in the disclosures. In addition, this ASU makes certain targeted improvements to simplify the application of hedge accounting guidance. This ASU is effective for fiscal years beginning after December 15, 2018, and interim periods within those fiscal years, and requires the modified retrospective approach. Early adoption is permitted. This update applies to all existing hedging relationships on the date of adoption with the cumulative effect of adoption being reflected as of the beginning of the fiscal year of adoption. The Company is still evaluating the impact this standard will have on its consolidated financial statements and related disclosures. In March 2017, the FASB issued ASU 2017-07, “Improving the Presentation of Net Periodic Pension Cost and Net Periodic Postretirement Benefit Cost.” The standard requires an employer to disaggregate the service cost component from the other components of net benefit cost and provides explicit guidance on the presentation of the service cost component and the other components of net benefit cost in the statements of income. The ASU is effective for annual periods beginning after December 15, 2017, including interim periods within those fiscal years, and should be applied retrospectively for the presentation of the service cost component and the other components of net periodic pension cost in the statements of income. Early adoption is permitted within the first interim period of the fiscal year. The Company is still evaluating the impact this standard will have on its consolidated financial statements and related disclosures. In January 2017, the FASB issued ASU 2017-04, “Simplifying the Test for Goodwill Impairment.” The standard simplifies the accounting for goodwill impairment by removing Step 2 of the goodwill impairment test, which requires a hypothetical purchase price allocation. This standard is effective for annual or interim goodwill impairment tests in fiscal years beginning after December 15, 2019, and will be applied on a prospective basis. Early adoption is permitted for interim or annual goodwill impairment tests performed on testing dates after January 1, 2017. The adoption of this standard is not expected to have a material impact on the Company’s consolidated financial statements and related disclosures. In January 2017, the FASB issued ASU 2017-01, “Clarifying the Definition of a Business.” The standard clarifies the definition of a business by adding guidance to assist entities in evaluating whether transactions should be accounted for as acquisitions of assets or businesses. This standard is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. Early adoption is permitted for certain transactions. The Company is still evaluating the impact this standard will have on its consolidated financial statements and related disclosures. In October 2016, the FASB issued ASU 2016-16, “Intra-Entity Transfers of Assets Other Than Inventory.” The standard requires the immediate recognition of tax effects for an intra-entity asset transfer other than inventory. This standard is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. Early adoption is permitted. The adoption of this standard is not expected to have a material impact on the Company’s consolidated financial statements and related disclosures. In February 2016, the FASB issued ASU 2016-02, “Leases.” The standard established the principles that lessees and lessors will apply to report useful information to users of financial statements about the amount, timing and uncertainty of cash flows arising from a lease. This standard is effective for fiscal years beginning after December 15, 2018, and interim periods within those fiscal years. Early adoption is permitted. The Company is still evaluating the full impact this standard will have on its consolidated financial statements and related disclosures, but expects to recognize substantially all of its leases on the balance sheet by recording a right-to-use asset and a corresponding lease liability. In May 2014, the FASB issued ASU 2014-09, “Revenue from Contracts with Customers.” The standard, including subsequently issued amendments, will replace most existing revenue recognition guidance in U.S. GAAP when it becomes effective and permits the use of either a modified retrospective or cumulative effect transition method. The standard will require an entity to recognize the amount of revenue to which it expects to be entitled for the transfer of promised goods or services to customers. The standard will be effective for annual and interim periods beginning after December 15, 2017. The Company formed an implementation team during fiscal year 2016 to oversee adoption of the new standard. The implementation team has completed its initial assessment of the new standard, including a detailed review of the Company’s contract portfolio, revenue streams to identify potential differences in accounting as a result of the new standard, and selected the modified retrospective transition method. The Company continues to assess the impact on the existing revenue accounting policies, newly required financial statement disclosures, and executing on the project plan. Currently, the Company is finalizing contract reviews, working through anticipated changes to systems and business processes, and internal controls to support the adoption of the new standard. The Company preliminarily expects certain changes in the timing of revenue recognition within the Manufacturing reportable segment, specifically within the Biologics business where revenue from certain studies will shift to recognition at a point in time instead of the current recognition over time. Other isolated changes to the timing of revenue recognition may be necessary in other businesses.

Business Acquisitions and Divestiture

9 Months Ended

Sep. 30, 2017

Business Combinations [Abstract]

BUSINESS ACQUISITIONS AND DIVESTITURE

Brains On-Line

On August 4, 2017, the Company acquired Brains On-Line, a leading contract research organization (CRO) providing critical data that advances novel therapeutics for the treatment of central nervous system (CNS) diseases. Brains On-Line strategically expands the Company’s existing CNS capabilities and establishes the Company as a single-source provider for a broad portfolio of discovery CNS services. The purchase price for Brains On-Line was $21.3 million in cash, subject to certain post-closing adjustments that may change the purchase price, and was funded by the Company’s various borrowings. In addition to the initial purchase price, the transaction includes aggregate, undiscounted contingent payments of up to €6.7 million (approximately $7.9 million based on current exchange rates), based on future performance. The Brains On-Line business is reported as part of the Company’s DSA reportable segment.

The contingent payments become payable based on the achievement of certain revenue and earnings targets. If achieved, the payments become due in the first quarter of fiscal year 2019. The Company estimated the fair value of this contingent consideration based on a probability-weighted set of outcomes.

The purchase price allocation of $20.6 million, net of $0.7 million of cash acquired, was as follows:



	August 4, 2017
	(in thousands)
Trade receivables (contractual amount of $1,146)	$	1,146
Other current assets (excluding cash)	670
Property, plant and equipment	664
Other long-term assets	13
Definite-lived intangible assets	9,300
Goodwill	12,324
Current liabilities	(863		)
Deferred revenue	(405		)
Long-term liabilities	(2,203		)
Total purchase price allocation	$	20,646

The purchase price allocation is subject to change as additional information becomes available concerning the fair value and tax basis of the assets acquired and liabilities assumed. Any additional adjustments to the purchase price allocation will be made as soon as practicable but no later than one year from the date of acquisition.

The breakout of definite-lived intangible assets acquired was as follows:



	Definite-Lived Intangible Assets		Weighted Average Amortization Life
	(in thousands)		(in years)
Client relationships	$	7,000	13
Other intangible assets	2,300		10
Total definite-lived intangible assets	$	9,300	12

The goodwill resulting from the transaction is primarily attributable to the potential growth of the Company’s DSA businesses from customers and technology introduced through Brains On-Line and the assembled workforce of the acquired business. The goodwill attributable to Brains On-Line is not deductible for tax purposes.

The Company incurred transaction and integration costs in connection with the acquisition of $1.2 million and $2.1 million for the three and nine months ended September 30, 2017, respectively, which were included in selling, general and administrative expenses, within the unaudited condensed consolidated statements of income.

Pro forma financial information as well as actual revenue and operating income have not been included because Brains On-Line’s financial results are not significant when compared to the Company’s consolidated financial results.

Agilux

On September 28, 2016, the Company acquired Agilux Laboratories, Inc. (Agilux), a CRO that provides a suite of integrated discovery bioanalytical services for small and large molecules, drug metabolism and pharmacokinetic services, and pharmacology services. The acquisition supports the Company’s strategy to offer clients a broader, integrated portfolio that provides services continuously from the earliest stages of drug research through the non-clinical development process. The purchase price for Agilux was $64.9 million in cash and was funded by borrowings on the Company’s revolving credit facility. The business is reported as part of the Company’s DSA reportable segment.

The purchase price allocation of $62.0 million, net of $2.9 million of cash acquired, was as follows:



	September 28, 2016
	(in thousands)
Trade receivables (contractual amount of $4,799)	$	4,799
Other current assets (excluding cash)	794
Property, plant and equipment	3,907
Other long-term assets	11
Definite-lived intangible assets	21,900
Goodwill	44,517
Current liabilities	(3,812		)
Long-term liabilities	(10,091		)
Total purchase price allocation	$	62,025

From the date of the acquisition through September 30, 2017, the Company recorded measurement-period adjustments related to the acquisition that resulted in an immaterial change to the purchase price allocation on a consolidated basis. No further adjustments will be made to the purchase price allocation.

The breakout of definite-lived intangible assets acquired was as follows:



	Definite-Lived Intangible Assets		Weighted Average Amortization Life
	(in thousands)		(in years)
Client relationships	$	16,700	17
Other intangible assets	5,200		4
Total definite-lived intangible assets	$	21,900	14

The goodwill resulting from the transaction is primarily attributable to the potential growth of the Company’s DSA businesses from customers and technology introduced through Agilux and the assembled workforce of the acquired business. The goodwill attributable to Agilux is not deductible for tax purposes.

The Company incurred zero and $0.3 million in transaction and integration costs in connection with the acquisition during the three and nine months ended September 30, 2017, respectively, which were included in selling, general and administrative expenses, within the unaudited condensed consolidated statements of income. The Company incurred $1.1 million in transaction and integration costs in connection with the acquisition during the three and nine months ended September 24, 2016, respectively, which were included in selling, general and administrative expenses, within the unaudited condensed consolidated statements of income.

Blue Stream

On June 27, 2016, the Company acquired Blue Stream Laboratories, Inc. (Blue Stream), an analytical CRO supporting the development of complex biologics and biosimilars. Combining Blue Stream with the Company’s existing discovery, safety assessment, and biologics capabilities created a leading CRO that has the ability to support biologic and biosimilar development from characterization through clinical testing and commercialization. The purchase price for Blue Stream was $11.7 million, including $3.0 million in contingent consideration, and was subject to certain customary adjustments. The acquisition was funded by borrowings on the Company’s revolving credit facility. The business is reported in the Company’s Manufacturing reportable segment.

The Company estimated the fair value of this contingent consideration based on a probability-weighted set of outcomes. The contingent consideration is a one-time payment payable based on the achievement of a revenue target. The target was achieved and the Company paid the contingent consideration in the third quarter of fiscal year 2017.

The purchase price allocation of $11.7 million, net of a non-significant amount of cash acquired, was as follows:



	June 27, 2016
	(in thousands)
Trade receivables (contractual amount of $1,104)	$	1,104
Other current assets (excluding cash)	15
Property, plant and equipment	912
Other long-term assets	187
Definite-lived intangible assets	1,230
Goodwill	10,334
Current liabilities	(1,132		)
Long-term liabilities	(901		)
Total purchase price allocation	$	11,749

The breakout of definite-lived intangible assets acquired was as follows:



	Definite-Lived Intangible Assets		Weighted Average Amortization Life
	(in thousands)		(in years)
Client relationships	$	650	10
Other intangible assets	580		5
Total definite-lived intangible assets	$	1,230	7

The goodwill resulting from the transaction is primarily attributable to the potential growth of the Company’s Manufacturing segment from customers and technology introduced through Blue Stream, the assembled workforce of the acquired business, expected synergies, and the development of future proprietary processes. The goodwill attributable to Blue Stream is not deductible for tax purposes.

The Company incurred non-significant transaction and integration costs in connection with the acquisition during the three and nine months ended September 30, 2017, which were included in selling, general and administrative expenses, within the unaudited condensed consolidated statements of income. The Company incurred a non-significant amount and $0.4 million of transaction and integration costs during the three and nine months ended September 24, 2016, respectively, which were included in selling, general and administrative expenses, within the unaudited condensed consolidated statements of income.

WIL Research

On April 4, 2016, the Company acquired WIL Research, a provider of safety assessment and CDMO services to biopharmaceutical, agricultural and industrial chemical companies worldwide. The acquisition enhanced the Company’s position as a leading, global, early-stage CRO by strengthening its ability to partner with clients across the drug discovery and development continuum. The purchase price for WIL Research was $604.8 million, including assumed liabilities of $0.4 million. The purchase price included payment for actual working capital of the acquired business. The acquisition was funded by cash on hand and borrowings on the Company’s $1.65B Credit Facility. See Note 7, “Long-Term Debt and Capital Lease Obligations.” WIL Research’s safety assessment and CDMO businesses are reported in the Company’s DSA and Manufacturing reportable segments, respectively. On February 10, 2017, the Company divested the CDMO business.

The purchase price allocation of $577.4 million, net of $27.4 million of cash acquired, was as follows:



	April 4, 2016
	(in thousands)
Trade receivables (contractual amount of $48,625)	$	48,157
Inventories	2,296
Other current assets (excluding cash)	3,814
Property, plant and equipment	129,066
Other long-term assets	1,060
Definite-lived intangible assets	164,800
Goodwill	330,175
Deferred revenue	(39,103		)
Other current liabilities	(27,386		)
Long-term liabilities	(35,488		)
Total purchase price allocation	$	577,391

The breakout of definite-lived intangible assets acquired was as follows:



	Definite-Lived Intangible Assets		Weighted Average Amortization Life
	(in thousands)		(in years)
Client relationships	$	137,500	15
Developed technology	20,700		3
Backlog	6,600		1
Total definite-lived intangible assets	$	164,800	13

The goodwill resulting from the transaction, $19.0 million of which was deductible for tax purposes due to a prior asset acquisition, was primarily attributed to the potential growth of the Company’s DSA and Manufacturing businesses from clients introduced through WIL Research, the assembled workforce of the acquired business, and expected cost synergies. Subsequent to the divestiture of the CDMO business on February 10, 2017, $14.8 million of the goodwill was deductible for tax purposes.

The Company incurred transaction and integration costs in connection with the acquisition of $0.4 million and $1.3 million for the three months ended September 30, 2017 and September 24, 2016, respectively, which were included in selling, general and administrative expenses, within the unaudited condensed consolidated statements of income. The Company incurred transaction and integration costs in connection with the acquisition of $1.6 million and $13.7 million for the nine months ended September 30, 2017 and September 24, 2016, respectively, which were included in selling, general and administrative expenses, within the unaudited condensed consolidated statements of income.

WIL Research revenue and operating income for the three months ended September 24, 2016 were $57.4 million and $3.6 million, respectively. WIL Research revenue and operating income for the nine months ended September 24, 2016 were $112.6 million and $4.6 million, respectively.

The following selected pro forma consolidated results of operations are presented as if the WIL Research acquisition had occurred as of the beginning of the period immediately preceding the period of acquisition after giving effect to certain adjustments. For the nine months ended September 24, 2016, these adjustments included additional amortization of intangible assets and depreciation of fixed assets of $1.4 million, reversal of interest expense on borrowings of $2.7 million, elimination of intercompany activity, and other one-time costs, and the tax impacts of these adjustments.



	September 24, 2016
	Three Months Ended		Nine Months Ended
	(in thousands, except per share amounts)
Revenue	$	425,720	$	1,275,175
Net income attributable to common shareholders	39,530		129,050
Earnings per common share
Basic	$	0.84	$	2.75
Diluted	$	0.82	$	2.70

These pro forma results of operations have been prepared for comparative purposes only, and they do not purport to be indicative of the results of operations that actually would have resulted had the acquisition occurred on the date indicated or that may result in the future. No effect has been given for synergies, if any, that may have been realized through the acquisition.

Contract Manufacturing

On February 10, 2017, the Company completed the divestiture of its CDMO business to Quotient Clinical Ltd., based in London, England, for $75.0 million in proceeds, net of $0.6 million in cash and cash equivalents transferred in conjunction with the sale and $0.3 million of working capital adjustments.

The CDMO business was acquired in April 2016 as part of the acquisition of WIL Research and was reported in the Company’s Manufacturing reportable segment. Following a strategic review that was finalized subsequent to December 31, 2016, the Company determined that the CDMO business was not optimized within the Company’s portfolio at its current scale, and that the capital could be better deployed in other long-term growth opportunities.

During the three months ended April 1, 2017, the Company recorded a gain on the divestiture of the CDMO business of $10.6 million, which was included in other income, net within the Company’s unaudited condensed consolidated statements of income. As of February 10, 2017, the carrying amounts of the major classes of assets and liabilities associated with the divestiture of the CDMO business were as follows (in thousands):



Assets
Current assets	$	5,505
Property, plant and equipment, net	11,174
Goodwill	35,857
Long-term assets	17,154
Total assets	$	69,690
Liabilities
Deferred revenue	$	4,878
Other current liabilities	1,158
Total liabilities	$	6,036

Supplemental Balance Sheet Information

9 Months Ended

Sep. 30, 2017

Supplemental Balance Sheet Information [Abstract]

SUPPLEMENTAL BALANCE SHEET INFORMATION

The composition of trade receivables, net is as follows:



	September 30, 2017			December 31, 2016
	(in thousands)
Client receivables	$	321,472		$	283,997
Unbilled revenue	103,389			82,203
Total	424,861			366,200
Less: Allowance for doubtful accounts	(2,526		)	(2,150		)
Trade receivables, net	$	422,335		$	364,050

The composition of inventories is as follows:



	September 30, 2017		December 31, 2016
	(in thousands)
Raw materials and supplies	$	19,256	$	18,893
Work in process	13,163		13,681
Finished products	74,953		63,259
Inventories	$	107,372	$	95,833

The composition of other current assets is as follows:



	September 30, 2017		December 31, 2016
	(in thousands)
Investments	$	30,351	$	3,771
Prepaid income taxes	55,416		40,705
Restricted cash	591		532
Other current assets	$	86,358	$	45,008

The composition of other assets is as follows:



	September 30, 2017		December 31, 2016
	(in thousands)
Life insurance policies	$	32,739	$	29,456
Venture capital investments	59,511		45,331
Restricted cash	1,944		1,736
Other	15,604		11,907
Other assets	$	109,798	$	88,430

The composition of other current liabilities is as follows:



	September 30, 2017		December 31, 2016
	(in thousands)
Accrued income taxes	$	32,931	$	25,621
Other	683		879
Other current liabilities	$	33,614	$	26,500

The composition of other long-term liabilities is as follows:



	September 30, 2017		December 31, 2016
	(in thousands)
Long-term pension liability	$	91,991	$	89,984
Accrued executive supplemental life insurance retirement plan and deferred compensation plan	33,926		32,880
Other	41,576		36,375
Other long-term liabilities	$	167,493	$	159,239

Venture Capital Investments	9 Months Ended
Venture Capital Investments	Sep. 30, 2017
Equity Method Investments and Joint Ventures [Abstract]
VENTURE CAPITAL INVESTMENTS	VENTURE CAPITAL INVESTMENTS The Company invests in several venture capital funds that invest in start-up companies, primarily in the life sciences industry. The Company’s ownership interest in these funds ranges from 0.7% to 12.1%. The Company accounts for the investments in limited partnerships (LPs), which are variable interest entities, under the equity or cost method of accounting. The Company is not the primary beneficiary because it has no power to direct the activities that most significantly affect the LPs’ economic performance. The Company accounts for the investments in limited liability companies, which are not variable interest entities, under the equity method of accounting. The Company’s total commitments to the venture capital funds as of September 30, 2017, were $87.7 million, of which the Company funded $48.0 million through that date. During the three and nine months ended September 30, 2017, the Company received dividends of $3.3 million and $7.7 million, respectively, from the funds. During each of the three and nine months ended September 24, 2016, the Company received dividends of $2.3 million from the funds. The Company recognized gains of $5.8 million and $0.4 million related to these investments for the three months ended September 30, 2017 and September 24, 2016, respectively. The Company recognized gains of $12.5 million and $8.5 million related to these investments for the nine months ended September 30, 2017 and September 24, 2016, respectively.

Fair Value

9 Months Ended

Sep. 30, 2017

Fair Value Disclosures [Abstract]

FAIR VALUE

The Company has certain assets and liabilities recorded at fair value, which have been classified as Level 1, 2, or 3 within the fair value hierarchy:


•	Level 1 - Fair values are determined utilizing prices (unadjusted) in active markets for identical assets or liabilities that the Company has the ability to access,


•	Level 2 - Fair values are determined by utilizing quoted prices for identical or similar assets and liabilities in active markets or other market observable inputs such as interest rates, yield curves, and foreign currency spot rates,


•	Level 3 - Prices or valuations that require inputs that are both significant to the fair value measurement and unobservable.

The fair value hierarchy level is determined by asset and liability class based on the lowest level of significant input. The observability of inputs may change for certain assets or liabilities. This condition could cause an asset or liability to be reclassified between levels. The Company recognizes transfers between levels within the fair value hierarchy, if any, at the end of each quarter. During the nine months ended September 30, 2017 and September 24, 2016, there were no transfers between levels.

Valuation methodologies used for assets and liabilities measured or disclosed at fair value are as follows:


•	Cash equivalents - Valued at market prices determined through third-party pricing services;


•	Mutual funds - Valued at the unadjusted quoted net asset value of shares held by the Company;


•	Foreign currency forward contracts - Valued using market observable inputs, such as forward foreign exchange points and foreign exchanges rates;


•	Life insurance policies - Valued at cash surrender value based on the fair value of underlying investments; and


•	Contingent consideration - Valued based on a probability weighting of the future cash flows associated with the potential outcomes.

Assets and liabilities measured at fair value on a recurring basis are summarized below:



	September 30, 2017
	Level 1		Level 2		Level 3		Total
	(in thousands)
Cash equivalents	$	—	$	21	$	—	$	21
Other assets:
Life insurance policies	—		25,218		—		25,218
Total assets measured at fair value	$	—	$	25,239	$	—	$	25,239

Other current liabilities:
Contingent consideration	$	—	$	—	$	296	$	296
Total liabilities measured at fair value	$	—	$	—	$	296	$	296



	December 31, 2016
	Level 1		Level 2		Level 3		Total
	(in thousands)
Cash equivalents	$	—	$	21	$	—	$	21
Other assets:
Life insurance policies	—		22,121		—		22,121
Total assets measured at fair value	$	—	$	22,142	$	—	$	22,142

Other current liabilities:
Contingent consideration	$	—	$	—	$	3,621	$	3,621
Total liabilities measured at fair value	$	—	$	—	$	3,621	$	3,621

Contingent Consideration

The following table provides a rollforward of the contingent consideration related to the business acquisitions. See Note 2, “Business Acquisitions and Divestiture.”



	Nine Months Ended
	September 30, 2017			September 24, 2016
	(in thousands)
Beginning balance	$	3,621		$	1,370
Additions	296			3,600
Payments	(3,606		)	(874		)
Total gains or losses (realized/unrealized):
Reversal of previously recorded contingent liability and change in fair value	(15		)	30
Ending balance	$	296		$	4,126

The unobservable inputs used in the fair value measurement of the Company’s contingent consideration are the probabilities of successful achievement of certain financial targets and a discount rate. Increases or decreases in any of the probabilities of success would result in a higher or lower fair value measurement, respectively. Increases or decreases in the discount rate would result in a lower or higher fair value measurement, respectively.

Debt Instruments

The book value of the Company’s term and revolving loans, which are variable rate loans carried at amortized cost, approximates the fair value based on current market pricing of similar debt. As the fair value is based on significant other observable inputs, including current interest and foreign currency exchange rates, it is deemed to be Level 2.

- Definition

The entire disclosure for the fair value of financial instruments (as defined), including financial assets and financial liabilities (collectively, as defined), and the measurements of those instruments as well as disclosures related to the fair value of non-financial assets and liabilities. Such disclosures about the financial instruments, assets, and liabilities would include: (1) the fair value of the required items together with their carrying amounts (as appropriate); (2) for items for which it is not practicable to estimate fair value, disclosure would include: (a) information pertinent to estimating fair value (including, carrying amount, effective interest rate, and maturity, and (b) the reasons why it is not practicable to estimate fair value; (3) significant concentrations of credit risk including: (a) information about the activity, region, or economic characteristics identifying a concentration, (b) the maximum amount of loss the entity is exposed to based on the gross fair value of the related item, (c) policy for requiring collateral or other security and information as to accessing such collateral or security, and (d) the nature and brief description of such collateral or security; (4) quantitative information about market risks and how such risks are managed; (5) for items measured on both a recurring and nonrecurring basis information regarding the inputs used to develop the fair value measurement; and (6) for items presented in the financial statement for which fair value measurement is elected: (a) information necessary to understand the reasons for the election, (b) discussion of the effect of fair value changes on earnings, (c) a description of [similar groups] items for which the election is made and the relation thereof to the balance sheet, the aggregate carrying value of items included in the balance sheet that are not eligible for the election; (7) all other required (as defined) and desired information.

+ References + Details

Goodwill and Intangible Assets

9 Months Ended

Sep. 30, 2017

Goodwill and Intangible Assets Disclosure [Abstract]

GOODWILL AND INTANGIBLE ASSETS

Goodwill

The following table provides a rollforward of the Company’s goodwill:



			Adjustments to Goodwill
	December 31, 2016		Acquisitions / (Divestitures)			Foreign Exchange		September 30, 2017
	(in thousands)
RMS	$	56,397	$	—		$	1,262	$	57,659
DSA	563,476		12,523			26,072		602,071
Manufacturing	167,644		(36,000		)	8,873		140,517
Total	$	787,517	$	(23,477	)	$	36,207	$	800,247

The increase in goodwill during the nine months ended September 30, 2017 related primarily to the acquisition of Brains On-Line in the DSA reportable segment, and the favorable impact of foreign exchange, partially offset by the divestiture of the CDMO business in the Manufacturing reportable segment.

Intangible Assets, Net

The following table displays intangible assets, net by major class:



	September 30, 2017							December 31, 2016
	Gross		Accumulated Amortization			Net		Gross		Accumulated Amortization			Net
	(in thousands)
Backlog	$	8,065	$	(7,751	)	$	314	$	8,370	$	(6,390	)	$	1,980
Technology	80,256		(23,865		)	56,391		71,425		(14,314		)	57,111
Trademarks and trade names	8,617		(4,417		)	4,200		8,177		(4,124		)	4,053
Other	17,404		(7,244		)	10,160		16,775		(5,628		)	11,147
Other intangible assets	114,342		(43,277		)	71,065		104,747		(30,456		)	74,291
Client relationships	535,814		(231,432		)	304,382		519,123		(198,966		)	320,157
Intangible assets	$	650,156	$	(274,709	)	$	375,447	$	623,870	$	(229,422	)	$	394,448

During the nine months ended September 30, 2017, the Company divested the CDMO business, which resulted in a net decrease of $16.8 million and $0.3 million to client relationships and backlog, respectively. During the three months ended March 26, 2016, the Company determined that the carrying values of certain DSA intangible assets were not recoverable and recorded an impairment charge of $1.9 million, which was included in costs of services provided (excluding amortization of intangible assets) within the unaudited condensed consolidated statements of income.

- Definition

The entire disclosure for the aggregate amount of goodwill and a description of intangible assets, which may include (a) for amortizable intangible assets (also referred to as finite-lived intangible assets), the carrying amount, the amount of any significant residual value, and the weighted-average amortization period, (b) for intangible assets not subject to amortization (also referred to as indefinite-lived intangible assets), the carrying amount, and (c) the amount of research and development assets acquired and written off in the period, including the line item in the income statement in which the amounts written off are aggregated, if not readily apparent from the income statement. Also discloses (a) for amortizable intangibles assets in total and by major class, the gross carrying amount and accumulated amortization, the total amortization expense for the period, and the estimated aggregate amortization expense for each of the five succeeding fiscal years, (b) for intangible assets not subject to amortization the carrying amount in total and by major class, and (c) for goodwill, in total and for each reportable segment, the changes in the carrying amount of goodwill during the period (including the aggregate amount of goodwill acquired, the aggregate amount of impairment losses recognized, and the amount of goodwill included in the gain (loss) on disposal of a reporting unit). If any part of goodwill has not been allocated to a reportable segment, discloses the unallocated amount and the reasons for not allocating. For each impairment loss recognized related to an intangible asset (excluding goodwill), discloses: (a) a description of the impaired intangible asset and the facts and circumstances leading to the impairment, (b) the amount of the impairment loss and the method for determining fair value, (c) the caption in the income statement or the statement of activities in which the impairment loss is aggregated, and (d) the segment in which the impaired intangible asset is reported. For each goodwill impairment loss recognized, discloses: (a) a description of the facts and circumstances leading to the impairment, (b) the amount of the impairment loss and the method of determining the fair value of the associated reporting unit, and (c) if a recognized impairment loss is an estimate not finalized and the reasons why the estimate is not final. May also disclose the nature and amount of any significant adjustments made to a previous estimate of an impairment loss.

+ References + Details

Long-Term Debt and Capital Lease Obligations

9 Months Ended

Sep. 30, 2017

Debt Disclosure [Abstract]

LONG-TERM DEBT AND CAPITAL LEASE OBLIGATIONS

Long-Term Debt

Long-term debt, net consists of the following:



	September 30, 2017			December 31, 2016
	(in thousands)
Term loans	$	609,375		$	633,750
Revolving credit facility	545,373			578,759
Other long-term debt	3,675			185
Total debt	1,158,423			1,212,694
Less: current portion of long-term debt	(24,481		)	(24,560		)
Long-term debt	1,133,942			1,188,134
Debt discount and debt issuance costs	(6,233		)	(7,633		)
Long-term debt, net	$	1,127,709		$	1,180,501

As of September 30, 2017 and December 31, 2016, the weighted average interest rate on the Company’s debt was 2.26% and 1.89%, respectively.

On March 30, 2016, the Company amended and restated its credit facility creating a $1.65 billion credit facility ($1.65B Credit Facility). In connection with the amendment and restatement, the Company expensed $1.0 million of debt issuance costs in the nine months ended September 24, 2016.

The $1.65B Credit Facility provides for a $650.0 million term loan and a $1.0 billion multi-currency revolving facility. The term loan facility matures in 19 quarterly installments with the last installment due March 30, 2021. The revolving facility matures on March 30, 2021, and requires no scheduled payment before that date. Under specified circumstances, the Company has the ability to increase the term loan and/or revolving facility by up to $500.0 million in the aggregate.

The interest rates applicable to the term loan and revolving facility under the $1.65B Credit Facility are, at the Company’s option, equal to either the base rate (which is the higher of (1) the prime rate, (2) the federal funds rate plus 0.50%, or (3) the one-month adjusted LIBOR rate plus 1.0%) or the adjusted LIBOR rate, plus an interest rate margin based upon the Company’s leverage ratio.

The $1.65B Credit Facility includes certain customary representations and warranties, events of default, notices of material adverse changes to the Company’s business and negative and affirmative covenants. These covenants include (1) maintenance of a ratio of consolidated earnings before interest, taxes, depreciation and amortization (EBITDA) less capital expenditures to consolidated cash interest expense, for any period of four consecutive fiscal quarters, of no less than 3.50 to 1.0 as well as (2) maintenance of a ratio of consolidated indebtedness to consolidated EBITDA for any period of four consecutive fiscal quarters, of no more than 3.75 to 1.0 with step downs to 3.50 to 1.0 by the last day of the three months ended December 30, 2017. As of September 30, 2017, the Company was compliant with all covenants.

The obligations of the Company under the $1.65B Credit Facility are collateralized by substantially all of the assets of the Company.

Letters of Credit

As of September 30, 2017 and December 31, 2016, the Company had $4.9 million in outstanding letters of credit.

Capital Lease Obligations

The Company’s capital lease obligations amounted to $30.9 million and $29.9 million as of September 30, 2017 and December 31, 2016, respectively.

Equity and Redeemable Noncontrolling Interest

9 Months Ended

Sep. 30, 2017

Equity [Abstract]

EQUITY AND REDEEMABLE NONCONTROLLING INTEREST

Earnings Per Share

The following table reconciles the numerator and denominator in the computations of basic and diluted earnings per share:



	Three Months Ended					Nine Months Ended
	September 30, 2017			September 24, 2016		September 30, 2017			September 24, 2016
	(in thousands)
Numerator:
Income from continuing operations, net of income taxes	$	52,994		$	37,691	$	154,630		$	110,811
Income (loss) from discontinued operations, net of income taxes	(39		)	342		(114		)	328
Less: Net income attributable to noncontrolling interests	481			298		1,312			1,054
Net income attributable to common shareholders	$	52,474		$	37,735	$	153,204		$	110,085

Denominator:
Weighted-average shares outstanding - Basic	47,451			47,160		47,530			46,954
Effect of dilutive securities:
Stock options, restricted stock units, performance share units and restricted stock	939			874		910			884
Weighted-average shares outstanding - Diluted	48,390			48,034		48,440			47,838

Options to purchase 0.4 million and 0.6 million shares for the three months ended September 30, 2017 and September 24, 2016, respectively, as well as an insignificant number of restricted shares, restricted stock units (RSUs), and performance share units (PSUs), were not included in computing diluted earnings per share because their inclusion would have been anti-dilutive. Options to purchase 0.6 million and 0.9 million shares for the nine months ended September 30, 2017 and September 24, 2016, respectively, as well as an insignificant number of restricted shares, RSUs, and PSUs, were not included in computing diluted earnings per share because their inclusion would have been anti-dilutive. Basic weighted-average shares outstanding for both the nine months ended September 30, 2017 and September 24, 2016 excluded the impact of 1.1 million shares of non-vested restricted stock and RSUs.

Treasury Shares

During the nine months ended September 30, 2017, the Company repurchased 1.0 million shares totaling $90.6 million under its authorized stock repurchase program. No shares were repurchased in the nine months ended September 24, 2016. On May 9, 2017, the Company’s Board of Directors increased the stock repurchase authorization by $150 million, to an aggregate amount of $1.3 billion. As of September 30, 2017, the Company had $129.1 million remaining on the authorized stock repurchase program. The Company’s stock-based compensation plans permit the netting of common stock upon vesting of restricted stock, RSUs, and PSUs in order to satisfy individual statutory tax withholding requirements. During the nine months ended September 30, 2017 and September 24, 2016, the Company acquired 0.2 million shares for $16.3 million and 0.2 million shares for $12.2 million, respectively, from such netting.

Accumulated Other Comprehensive Income

Changes to each component of accumulated other comprehensive income, net of income taxes, are as follows:



	Foreign Currency Translation Adjustment and Other			Pension and Other Post-Retirement Benefit Plans			Total
	(in thousands)
December 31, 2016	$	(154,595	)	$	(99,169	)	$	(253,764	)
Other comprehensive loss before reclassifications	68,590			—			68,590
Amounts reclassified from accumulated other comprehensive income (loss)	—			2,638			2,638
Net current period other comprehensive income	68,590			2,638			71,228
Income tax expense	—			776			776
September 30, 2017	$	(86,005	)	$	(97,307	)	$	(183,312	)

Nonredeemable Noncontrolling Interest

The Company has an investment in an entity whose financial results are consolidated in the Company’s financial statements, as it has the ability to exercise control over this entity. The interest of the noncontrolling party in this entity has been recorded as noncontrolling interest. The activity within the nonredeemable noncontrolling interest during the three months ended September 30, 2017 and September 24, 2016 was $0.3 million and $0.1 million, respectively. The activity within the nonredeemable noncontrolling interest during the nine months ended September 30, 2017 and September 24, 2016 was $0.8 million and $0.4 million, respectively.

Redeemable Noncontrolling Interest

The Company’s redeemable noncontrolling interest resulted from an acquisition of a 75% ownership interest in Vital River in January 2013 and a purchase of an additional 12% equity interest in Vital River in July 2016, totaling an ownership of 87%. Prior to the purchase of an additional 12% equity interest on July 7, 2016, the redeemable noncontrolling interest was reported at fair value.

Concurrent with the purchase of an additional equity interest, the original agreement was amended providing the Company with the right to purchase, and the noncontrolling interest holders with the right to sell, the remaining 13% equity interest at a contractually defined redemption value, subject to a redemption floor (embedded derivative). These rights are exercisable beginning in 2019 and are accelerated in certain events. The redeemable noncontrolling interest is measured at the greater of the amount that would be paid if settlement occurred as of the balance sheet date based on the contractually defined redemption value ($15.0 million as of September 30, 2017) and its carrying amount adjusted for net income (loss) attributable to the noncontrolling interest. As the noncontrolling interest holders have the ability to require the Company to purchase the remaining 13% interest, the noncontrolling interest is classified in the mezzanine section of the unaudited condensed consolidated balance sheets, which is presented above the equity section and below liabilities. The agreement does not limit the amount that the Company could be required to pay to purchase the remaining 13% equity interest.

The following table provides a rollforward of the activity related to the Company’s redeemable noncontrolling interest:



	Nine Months Ended
	September 30, 2017		September 24, 2016
	(in thousands)
Beginning balance	$	14,659	$	28,008
Purchase of 12% equity interest	—		(12,360		)
Total gains or losses (realized/unrealized):
Net income attributable to noncontrolling interest	474		462
Foreign currency translation	652		(875		)
Modification of 13% purchase option	—		1,495
Change in fair value, included in additional paid-in capital	—		(1,690		)
Ending balance	$	15,785	$	15,040

Income Taxes	9 Months Ended
Income Taxes	Sep. 30, 2017
Income Tax Disclosure [Abstract]
INCOME TAXES	INCOME TAXES The Company’s effective tax rate for the three months ended September 30, 2017 and September 24, 2016 was 27.3% and 29.2%, respectively. The Company’s effective tax rate for the nine months ended September 30, 2017 and September 24, 2016 was 32.2% and 30.4%, respectively. For the three months ended September 30, 2017, the decrease was primarily attributable to a tax benefit of $1.2 million related to the settlement of competent authority proceedings, and the excess tax benefit associated with stock compensation of $0.9 million as a result of the adoption of ASU 2016-09. For the nine months ended September 30, 2017, the increase was primarily attributable to the tax on the gain on the divestiture of the CDMO business of $18.0 million, offset by the excess tax benefit associated with stock compensation of $9.7 million as a result of the adoption of ASU 2016-09. During the three months ended September 30, 2017, the Company’s unrecognized income tax benefits decreased by $0.8 million to $25.2 million, primarily due to the settlement of competent authority proceedings offset by unfavorable foreign exchange movement. The amount of unrecognized income tax benefits that would impact the effective tax rate increased by $0.3 million to $23.2 million. As of September 30, 2017, the amount of accrued interest and penalties on unrecognized tax benefits was $2.6 million. The Company estimates that it is reasonably possible that the unrecognized tax benefits will decrease by up to $0.9 million over the next twelve-month period, primarily as a result of the outcome of a pending tax ruling. The Company conducts business in a number of tax jurisdictions. As a result, it is subject to tax audits in jurisdictions including the U.S., U.K., China, Japan, France, Germany, and Canada. With few exceptions, the Company is no longer subject to U.S. and international income tax examinations for years before 2013. The Company and certain of its subsidiaries have ongoing tax controversies with various tax authorities in the U.S., Canada, Germany, and France. The Company does not believe that resolution of these controversies will have a material impact on its financial position or results of operations. In accordance with the Company’s policy, the remaining undistributed earnings of its non-U.S. subsidiaries remain indefinitely reinvested as of September 30, 2017, as they are required to fund needs outside the U.S. and cannot be repatriated in a manner that is substantially tax free. Income tax expense related to changes in unrecognized pension gains, losses, and prior service costs was $0.2 million and $0.1 million for the three months ended September 30, 2017 and September 24, 2016, respectively. Income tax expense related to changes in unrecognized pension gains, losses, and prior service costs was $0.8 million and $0.4 million for the nine months ended September 30, 2017 and September 24, 2016, respectively.

Pension and Other Post-Retirement Benefit Plans

9 Months Ended

Sep. 30, 2017

Retirement Benefits [Abstract]

PENSION AND OTHER POST-RETIREMENT BENEFIT PLANS

The following table provides the components of net periodic cost for the Company’s pension, deferred compensation and executive supplemental life insurance retirement plans:



	Three Months Ended						Nine Months Ended
	September 30, 2017			September 24, 2016			September 30, 2017			September 24, 2016
	(in thousands)
Service cost	$	749		$	655		$	2,277		$	1,848
Interest cost	2,663			2,773			8,428			9,357
Expected return on plan assets	(3,476		)	(3,038		)	(10,411		)	(11,028		)
Amortization of prior service credit	(134		)	(142		)	(392		)	(430		)
Amortization of net loss	1,017			503			3,030			1,594
Settlements	—			788			—			788
Net periodic cost	$	819		$	1,539		$	2,932		$	2,129

The net periodic cost for the Company’s post-retirement benefit plan for the three and nine months ended September 30, 2017 and September 24, 2016 was not significant.

Stock-Based Compensation

9 Months Ended

Sep. 30, 2017

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

STOCK-BASED COMPENSATION

The Company has stock-based compensation plans under which employees and non-employee directors may be granted stock-based awards such as stock options, restricted stock, RSUs, and PSUs.

The following table provides stock-based compensation by the financial statement line item in which it is reflected:



	Three Months Ended						Nine Months Ended
	September 30, 2017			September 24, 2016			September 30, 2017			September 24, 2016
	(in thousands)
Cost of revenue	$	1,700		$	1,608		$	4,989		$	4,957
Selling, general and administrative	9,826			8,992			27,913			27,690
Stock-based compensation, before income taxes	11,526			10,600			32,902			32,647
Provision for income taxes	(4,099		)	(3,785		)	(11,683		)	(11,653		)
Stock-based compensation, net of income taxes	$	7,427		$	6,815		$	21,219		$	20,994

During the nine months ended September 30, 2017, the Company granted stock options representing 0.6 million common shares with a per-share weighted-average grant date fair value of $18.30, RSUs representing 0.2 million common shares with a per-share weighted-average grant date fair value of $88.52, and PSUs representing 0.2 million common shares with a per-share weighted-average grant date fair value of $99.24. The maximum number of common shares to be issued upon vesting of PSUs granted during the nine months ended September 30, 2017 is 0.4 million.

Foreign Currency Contracts

9 Months Ended

Sep. 30, 2017

Derivative Instruments and Hedging Activities Disclosure [Abstract]

FOREIGN CURRENCY CONTRACTS

The Company enters into foreign exchange forward contracts to limit its foreign currency exposure related to intercompany loans that are not of a long-term investment nature. These contracts are recorded at fair value in the Company’s unaudited condensed consolidated balance sheets and are not designated as hedging instruments. Any gains or losses on such contracts are immediately recognized in other income, net, and are largely offset by the remeasurement of the underlying intercompany loan balances.

The Company did not have any foreign currency contracts open as of September 30, 2017 and December 31, 2016.

The following table summarizes gains recognized on foreign exchange forward contracts related to intercompany loans denominated in Euros on the Company’s unaudited condensed consolidated statements of income:



	Three Months Ended				Nine Months Ended
Location of Gain	September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
Other income, net	$	—	$	—	$	—	$	3,373

Commitments and Contingencies	9 Months Ended
Commitments and Contingencies	Sep. 30, 2017
Commitments and Contingencies Disclosure [Abstract]
COMMITMENTS AND CONTINGENCIES	COMMITMENTS AND CONTINGENCIES Litigation Various lawsuits, claims and proceedings of a nature considered normal to its business are pending against the Company. While the outcome of any of these proceedings cannot be accurately predicted, the Company does not believe the ultimate resolution of any of these existing matters would have a material adverse effect on the Company’s business or financial condition. Lease Commitments During the nine months ended September 30, 2017, the Company assumed or entered into new lease agreements or exercised options to extend the lease terms for certain existing leases. As a result, the Company’s lease obligations through 2032 increased by $37.9 million during the nine months ended September 30, 2017.

Restructuring and Asset Impairment Restructuring and Asset Impairment

9 Months Ended

Sep. 30, 2017

Restructuring and Related Activities [Abstract]

RESTRUCTURING AND ASSET IMPAIRMENT

RESTRUCTURING AND ASSET IMPAIRMENTS

Workforce Reductions

In recent fiscal years, the Company has been undertaking productivity improvement initiatives at various facilities. The following table provides a rollforward of the Company’s severance and transition costs liabilities related to those initiatives:



	Three Months Ended						Nine Months Ended
	September 30, 2017			September 24, 2016			September 30, 2017			September 24, 2016
	(in thousands)
Beginning balance	$	4,004		$	3,678		$	3,680		$	2,969
Expense	690			4,015			2,900			8,135
Payments / utilization	(991		)	(2,323		)	(3,084		)	(5,676		)
Foreign currency adjustments	103			2			310			(56		)
Ending balance	$	3,806		$	5,372		$	3,806		$	5,372

As of September 30, 2017, $3.4 million of severance and other personnel related costs liabilities were included in accrued compensation within the Company’s unaudited condensed consolidated balance sheets.

The following table presents severance and transition costs by classification within the unaudited condensed consolidated statements of income:



	Three Months Ended				Nine Months Ended
	September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
Cost of services provided and products sold (excluding amortization of intangible assets)	$	240	$	3,985	$	1,717	$	4,478
Selling, general and administrative	450		30		1,183		3,657
Total severance and transition costs	$	690	$	4,015	$	2,900	$	8,135

The following presents severance and transition related costs by reportable segment:



	Three Months Ended					Nine Months Ended
	September 30, 2017			September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
RMS	$	108		$	618	$	291	$	618
DSA	135			3,367		675		7,487
Manufacturing	472			30		1,799		30
Unallocated corporate	(25		)	—		135		—
Total severance and transition costs	$	690		$	4,015	$	2,900	$	8,135

Facilities

During the three months ended September 30, 2017, the Company continued the consolidation of certain DSA facilities in the U.S., Ireland, and the U.K. As a result, the Company recorded an asset impairment charge of $0.1 million and accelerated depreciation charges of $0.1 million related to the consolidation plans. During the three months ended September 24, 2016, the Company recorded an asset impairment charge of $4.3 million, other costs of $0.8 million, and accelerated depreciation charges of $0.1 million related to these activities. During the nine months ended September 30, 2017, the Company recorded other costs of $0.4 million, asset impairment charges of $0.3 million, and accelerated depreciation charges of $0.2 million related to the consolidation plans. During the nine months ended September 24, 2016, the Company recorded an asset impairment charge of $4.3 million, other costs of $0.8 million, and accelerated depreciation charges of $0.5 million related to these activities.

On November 8, 2017, as part of the Company’s efficiency initiatives, the Company committed to a plan to close its RMS production facility in Maryland before the end of 2018 and consolidate production in other facilities. The plan will result in costs incurred in the range of $18 million to $24 million in the fourth quarter of 2017 through fiscal 2018, primarily related to asset impairments (up to approximately $17 million), accelerated lease obligations (up to approximately $5 million), as well as severance, accelerated depreciation, and site consolidation costs. The majority of the costs are non-cash and are expected to be incurred in the fourth quarter of 2017. The cash portion of the costs are not expected to exceed $6 million.

Segment Information

9 Months Ended

Sep. 30, 2017

Segment Reporting [Abstract]

SEGMENT INFORMATION

The Company’s three reportable segments are Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Support (Manufacturing).

The following table presents revenue and other financial information by reportable segment:



	Three Months Ended				Nine Months Ended
	September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
RMS
Revenue	$	122,020	$	120,928	$	373,183	$	369,325
Operating income	30,726		31,224		102,016		103,055
Depreciation and amortization	5,272		5,245		15,309		15,613
Capital expenditures	6,762		2,532		13,769		5,966
DSA
Revenue	$	246,946	$	215,817	$	726,796	$	594,859
Operating income	46,616		31,303		136,966		94,514
Depreciation and amortization	20,333		20,671		58,667		51,228
Capital expenditures	10,127		4,509		25,552		13,860
Manufacturing
Revenue	$	95,266	$	88,975	$	279,145	$	250,459
Operating income	31,923		26,711		87,565		73,447
Depreciation and amortization	5,572		6,181		17,321		18,682
Capital expenditures	2,879		1,862		7,111		8,247

For the three months ended September 30, 2017 and September 24, 2016, reconciliations of segment operating income, depreciation and amortization, and capital expenditures to the respective consolidated amounts are as follows:



	Operating Income						Depreciation and Amortization				Capital Expenditures
	September 30, 2017			September 24, 2016			September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
Total reportable segments	$	109,265		$	89,238		$	31,177	$	32,097	$	19,768	$	8,903
Unallocated corporate	(35,281		)	(30,443		)	2,288		2,011		2,243		665
Total consolidated	$	73,984		$	58,795		$	33,465	$	34,108	$	22,011	$	9,568

For the nine months ended September 30, 2017 and September 24, 2016, reconciliations of segment operating income, depreciation and amortization, and capital expenditures to the respective consolidated amounts are as follows:



	Operating Income						Depreciation and Amortization				Capital Expenditures
	September 30, 2017			September 24, 2016			September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
Total reportable segments	$	326,547		$	271,016		$	91,297	$	85,523	$	46,432	$	28,073
Unallocated corporate	(101,781		)	(102,688		)	6,378		5,593		7,496		1,536
Total consolidated	$	224,766		$	168,328		$	97,675	$	91,116	$	53,928	$	29,609

Revenue for each significant product or service offering is as follows:



	Three Months Ended				Nine Months Ended
	September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
RMS	$	122,020	$	120,928	$	373,183	$	369,325
DSA	246,946		215,817		726,796		594,859
Manufacturing	95,266		88,975		279,145		250,459
Total revenue	$	464,232	$	425,720	$	1,379,124	$	1,214,643

A summary of unallocated corporate expense consists of the following:



	Three Months Ended				Nine Months Ended
	September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
Stock-based compensation	$	7,255	$	6,739	$	20,259	$	20,593
Compensation, benefits, and other employee-related expenses	11,771		9,048		37,812		29,327
External consulting and other service expenses	6,729		4,545		16,581		16,377
Information technology	3,237		2,903		9,247		8,399
Depreciation	2,287		2,011		6,378		5,593
Acquisition and integration	1,327		2,033		2,539		13,056
Other general unallocated corporate	2,675		3,164		8,965		9,343
Total unallocated corporate expense	$	35,281	$	30,443	$	101,781	$	102,688

Other general unallocated corporate expense consists of various departmental costs including those associated with departments such as senior executives, corporate accounting, legal, tax, human resources, treasury, and investor relations.

Basis of Presentation - Significant Accounting Policies (Policies)	9 Months Ended
	Sep. 30, 2017
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Use of Estimates	The preparation of unaudited condensed consolidated financial statements in accordance with U.S. GAAP requires that the Company make estimates and judgments that may affect the reported amounts of assets, liabilities, redeemable noncontrolling interest, revenues, expenses and related disclosure of contingent assets and liabilities. On an on-going basis, the Company evaluates its estimates, judgments, and methodologies. The Company bases its estimates on historical experience and on various other assumptions that are believed to be reasonable, the results of which form the basis for making judgments about the carrying values of assets and liabilities. Actual results may differ from these estimates under different assumptions or conditions. Changes in estimates are reflected in reported results in the period in which they become known.
Consolidation	The Company’s unaudited condensed consolidated financial statements reflect its financial statements and those of its subsidiaries in which the Company holds a controlling financial interest. For consolidated entities in which the Company owns or is exposed to less than 100% of the economics, the Company records net income (loss) attributable to noncontrolling interests in its consolidated statements of income equal to the percentage of the economic or ownership interest retained in such entities by the respective noncontrolling parties. Intercompany balances and transactions are eliminated in consolidation.
Fiscal Period	The Company’s fiscal year is typically based on a 52-week year, with each quarter composed of 13 weeks ending on the last Saturday on, or closest to, March 31, June 30, September 30, and December 31. A 53^rd week was included in the fourth quarter of fiscal year 2016, which is occasionally necessary to align with a December 31 calendar year end.
Newly Adopted and Issued Accounting Pronouncements	In November 2016, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) 2016-18, “Restricted Cash.” The standard addresses the classification and presentation of restricted cash and restricted cash equivalents within the statement of cash flows. The Company elected to early adopt this standard in fiscal year 2017 and applied the changes retrospectively to all prior periods presented in its unaudited condensed consolidated statements of cash flows. The Company historically excluded restricted cash balances, recorded in current and long-term other assets, from cash and cash equivalents within the unaudited condensed consolidated statements of cash flows, reflecting transfers between cash, cash equivalents, and restricted cash as a cash flow classified within cash flows relating to operating activities. As a result of the adoption of this standard, the Company combined restricted cash balances of $2.4 million and $2.0 million as of September 24, 2016, and December 26, 2015, respectively, with cash and cash equivalents when reconciling the beginning and ending balances within the unaudited condensed consolidated statements of cash flows for the nine months ended September 24, 2016. In August 2016, the FASB issued ASU 2016-15, “Classification of Certain Cash Receipts and Cash Payments.” The standard addresses the classification of certain transactions within the statement of cash flows, including cash payments for debt prepayment or debt extinguishment costs, contingent consideration payments made after a business combination, and distributions received from equity method investments. The Company elected to early adopt this standard in fiscal year 2017 and applied the changes retrospectively to all prior periods presented within its unaudited condensed consolidated statements of cash flows. As a result of the adoption of this standard, the Company reclassified $2.2 million from investing activities to operating activities within the unaudited condensed consolidated statements of cash flows for the nine months ended September 24, 2016. In March 2016, the FASB issued ASU 2016-09, “Improvements to Employee Share-Based Payment Accounting.” The standard reduces complexity in several aspects of the accounting for employee share-based compensation, including the income tax consequences, classification of awards as either equity or liabilities, and classification within the statement of cash flows. The Company adopted this standard in fiscal year 2017, and applied the changes as required by each amendment to its unaudited condensed consolidated financial statements and related disclosures. Under ASU 2016-09, the Company adopted the amendment to recognize excess tax benefits and tax deficiencies in the consolidated statements of income on a prospective basis, to present excess tax benefits within operating activities within the unaudited condensed consolidated statements of cash flows on a retrospective basis, and elected to change its accounting policy to account for forfeitures as they occur on a modified retrospective basis. The adoption to recognize excess tax benefits and tax deficiencies within the unaudited condensed consolidated statements of income on a prospective basis could result in fluctuations in the effective tax rate period-over-period, depending on how many awards vest and the volatility of the Company’s stock price. During the three months ended September 30, 2017, the impact to the provision for income taxes within the unaudited condensed consolidated statements of income was an excess tax benefit of $0.9 million. During the nine months ended September 30, 2017, the impact on the provision for income taxes within the unaudited condensed consolidated statements of income was an excess tax benefit of $9.7 million. Further, for the three and nine months ended September 30, 2017, the Company excluded the effect of windfall tax benefits from the hypothetical proceeds used to calculate the repurchase of shares under the treasury stock method for the calculation of diluted earnings per share. The adoption of the amendment to present excess tax benefits within operating activities within the unaudited condensed consolidated statements of cash flows on a retrospective basis resulted in the reclassification of a cash inflow of $9.5 million from cash provided by financing activities to cash provided by operating activities for the nine months ended September 24, 2016. The Company had previously classified cash paid for tax withholding purposes as a financing activity within the unaudited condensed consolidated statements of cash flows; therefore, there was no change related to this requirement under the amendment. The Company’s election to change its accounting policy to account for forfeitures when they occur on a modified retrospective basis resulted in an immaterial impact on its unaudited condensed consolidated financial statements and related disclosures. Newly Issued Accounting Pronouncements In August 2017, the FASB issued ASU 2017-12, “Derivatives and Hedging (Topic 815) Targeted Improvements to Accounting for Hedging Activities.” ASU 2017-12 refines and expands hedge accounting for both financial and commodity risks. It also creates more transparency around how economic results are presented, both on the face of the financial statements and in the disclosures. In addition, this ASU makes certain targeted improvements to simplify the application of hedge accounting guidance. This ASU is effective for fiscal years beginning after December 15, 2018, and interim periods within those fiscal years, and requires the modified retrospective approach. Early adoption is permitted. This update applies to all existing hedging relationships on the date of adoption with the cumulative effect of adoption being reflected as of the beginning of the fiscal year of adoption. The Company is still evaluating the impact this standard will have on its consolidated financial statements and related disclosures. In March 2017, the FASB issued ASU 2017-07, “Improving the Presentation of Net Periodic Pension Cost and Net Periodic Postretirement Benefit Cost.” The standard requires an employer to disaggregate the service cost component from the other components of net benefit cost and provides explicit guidance on the presentation of the service cost component and the other components of net benefit cost in the statements of income. The ASU is effective for annual periods beginning after December 15, 2017, including interim periods within those fiscal years, and should be applied retrospectively for the presentation of the service cost component and the other components of net periodic pension cost in the statements of income. Early adoption is permitted within the first interim period of the fiscal year. The Company is still evaluating the impact this standard will have on its consolidated financial statements and related disclosures. In January 2017, the FASB issued ASU 2017-04, “Simplifying the Test for Goodwill Impairment.” The standard simplifies the accounting for goodwill impairment by removing Step 2 of the goodwill impairment test, which requires a hypothetical purchase price allocation. This standard is effective for annual or interim goodwill impairment tests in fiscal years beginning after December 15, 2019, and will be applied on a prospective basis. Early adoption is permitted for interim or annual goodwill impairment tests performed on testing dates after January 1, 2017. The adoption of this standard is not expected to have a material impact on the Company’s consolidated financial statements and related disclosures. In January 2017, the FASB issued ASU 2017-01, “Clarifying the Definition of a Business.” The standard clarifies the definition of a business by adding guidance to assist entities in evaluating whether transactions should be accounted for as acquisitions of assets or businesses. This standard is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. Early adoption is permitted for certain transactions. The Company is still evaluating the impact this standard will have on its consolidated financial statements and related disclosures. In October 2016, the FASB issued ASU 2016-16, “Intra-Entity Transfers of Assets Other Than Inventory.” The standard requires the immediate recognition of tax effects for an intra-entity asset transfer other than inventory. This standard is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. Early adoption is permitted. The adoption of this standard is not expected to have a material impact on the Company’s consolidated financial statements and related disclosures. In February 2016, the FASB issued ASU 2016-02, “Leases.” The standard established the principles that lessees and lessors will apply to report useful information to users of financial statements about the amount, timing and uncertainty of cash flows arising from a lease. This standard is effective for fiscal years beginning after December 15, 2018, and interim periods within those fiscal years. Early adoption is permitted. The Company is still evaluating the full impact this standard will have on its consolidated financial statements and related disclosures, but expects to recognize substantially all of its leases on the balance sheet by recording a right-to-use asset and a corresponding lease liability. In May 2014, the FASB issued ASU 2014-09, “Revenue from Contracts with Customers.” The standard, including subsequently issued amendments, will replace most existing revenue recognition guidance in U.S. GAAP when it becomes effective and permits the use of either a modified retrospective or cumulative effect transition method. The standard will require an entity to recognize the amount of revenue to which it expects to be entitled for the transfer of promised goods or services to customers. The standard will be effective for annual and interim periods beginning after December 15, 2017. The Company formed an implementation team during fiscal year 2016 to oversee adoption of the new standard. The implementation team has completed its initial assessment of the new standard, including a detailed review of the Company’s contract portfolio, revenue streams to identify potential differences in accounting as a result of the new standard, and selected the modified retrospective transition method. The Company continues to assess the impact on the existing revenue accounting policies, newly required financial statement disclosures, and executing on the project plan. Currently, the Company is finalizing contract reviews, working through anticipated changes to systems and business processes, and internal controls to support the adoption of the new standard. The Company preliminarily expects certain changes in the timing of revenue recognition within the Manufacturing reportable segment, specifically within the Biologics business where revenue from certain studies will shift to recognition at a point in time instead of the current recognition over time. Other isolated changes to the timing of revenue recognition may be necessary in other businesses.

Business Acquisitions and Divestiture (Tables)

9 Months Ended

Sep. 30, 2017

Business Combinations [Abstract]

Summary of Purchase Price Allocation

The purchase price allocation of $20.6 million, net of $0.7 million of cash acquired, was as follows:



	August 4, 2017
	(in thousands)
Trade receivables (contractual amount of $1,146)	$	1,146
Other current assets (excluding cash)	670
Property, plant and equipment	664
Other long-term assets	13
Definite-lived intangible assets	9,300
Goodwill	12,324
Current liabilities	(863		)
Deferred revenue	(405		)
Long-term liabilities	(2,203		)
Total purchase price allocation	$	20,646

The purchase price allocation of $62.0 million, net of $2.9 million of cash acquired, was as follows:



	September 28, 2016
	(in thousands)
Trade receivables (contractual amount of $4,799)	$	4,799
Other current assets (excluding cash)	794
Property, plant and equipment	3,907
Other long-term assets	11
Definite-lived intangible assets	21,900
Goodwill	44,517
Current liabilities	(3,812		)
Long-term liabilities	(10,091		)
Total purchase price allocation	$	62,025

The purchase price allocation of $577.4 million, net of $27.4 million of cash acquired, was as follows:



	April 4, 2016
	(in thousands)
Trade receivables (contractual amount of $48,625)	$	48,157
Inventories	2,296
Other current assets (excluding cash)	3,814
Property, plant and equipment	129,066
Other long-term assets	1,060
Definite-lived intangible assets	164,800
Goodwill	330,175
Deferred revenue	(39,103		)
Other current liabilities	(27,386		)
Long-term liabilities	(35,488		)
Total purchase price allocation	$	577,391

The purchase price allocation of $11.7 million, net of a non-significant amount of cash acquired, was as follows:



	June 27, 2016
	(in thousands)
Trade receivables (contractual amount of $1,104)	$	1,104
Other current assets (excluding cash)	15
Property, plant and equipment	912
Other long-term assets	187
Definite-lived intangible assets	1,230
Goodwill	10,334
Current liabilities	(1,132		)
Long-term liabilities	(901		)
Total purchase price allocation	$	11,749

Definite-Lived Intangible Assets Acquired as Part of Business Combination

The breakout of definite-lived intangible assets acquired was as follows:



	Definite-Lived Intangible Assets		Weighted Average Amortization Life
	(in thousands)		(in years)
Client relationships	$	16,700	17
Other intangible assets	5,200		4
Total definite-lived intangible assets	$	21,900	14

The breakout of definite-lived intangible assets acquired was as follows:



	Definite-Lived Intangible Assets		Weighted Average Amortization Life
	(in thousands)		(in years)
Client relationships	$	7,000	13
Other intangible assets	2,300		10
Total definite-lived intangible assets	$	9,300	12

The breakout of definite-lived intangible assets acquired was as follows:



	Definite-Lived Intangible Assets		Weighted Average Amortization Life
	(in thousands)		(in years)
Client relationships	$	137,500	15
Developed technology	20,700		3
Backlog	6,600		1
Total definite-lived intangible assets	$	164,800	13

The breakout of definite-lived intangible assets acquired was as follows:



	Definite-Lived Intangible Assets		Weighted Average Amortization Life
	(in thousands)		(in years)
Client relationships	$	650	10
Other intangible assets	580		5
Total definite-lived intangible assets	$	1,230	7

Business Acquisition, Pro Forma Information

For the nine months ended September 24, 2016, these adjustments included additional amortization of intangible assets and depreciation of fixed assets of $1.4 million, reversal of interest expense on borrowings of $2.7 million, elimination of intercompany activity, and other one-time costs, and the tax impacts of these adjustments.



	September 24, 2016
	Three Months Ended		Nine Months Ended
	(in thousands, except per share amounts)
Revenue	$	425,720	$	1,275,175
Net income attributable to common shareholders	39,530		129,050
Earnings per common share
Basic	$	0.84	$	2.75
Diluted	$	0.82	$	2.70

Carrying Amounts of Assets and Liabilities

As of February 10, 2017, the carrying amounts of the major classes of assets and liabilities associated with the divestiture of the CDMO business were as follows (in thousands):



Assets
Current assets	$	5,505
Property, plant and equipment, net	11,174
Goodwill	35,857
Long-term assets	17,154
Total assets	$	69,690
Liabilities
Deferred revenue	$	4,878
Other current liabilities	1,158
Total liabilities	$	6,036

- Definition

Tabular disclosure of information related to a disposal group. Includes, but is not limited to, a discontinued operation, disposal classified as held-for-sale or disposed of by means other than sale or disposal of an individually significant component.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 45
-Paragraph 11
-URI http://asc.fasb.org/extlink&oid=65878427&loc=SL51721533-107759

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 4B
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721665-107760

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=64827811&loc=d3e1474-107760

Reference 4: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=64827811&loc=d3e1361-107760

Reference 5: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 7
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721683-107760

Reference 6: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 3A
-URI http://asc.fasb.org/extlink&oid=84176398&loc=SL51724579-110230

Reference 7: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5C
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721675-107760

Reference 8: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 4A
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721663-107760

Reference 9: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=84176398&loc=d3e2941-110230

Reference 10: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5B
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721673-107760

Reference 11: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 3A
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721659-107760

Reference 12: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5A
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721671-107760

Reference 13: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5D
-URI http://asc.fasb.org/extlink&oid=64827811&loc=SL51721677-107760

+ Details

Supplemental Balance Sheet Information (Tables)

9 Months Ended

Sep. 30, 2017

Supplemental Balance Sheet Information [Abstract]

Composition of Net Trade Receivables

The composition of trade receivables, net is as follows:



	September 30, 2017			December 31, 2016
	(in thousands)
Client receivables	$	321,472		$	283,997
Unbilled revenue	103,389			82,203
Total	424,861			366,200
Less: Allowance for doubtful accounts	(2,526		)	(2,150		)
Trade receivables, net	$	422,335		$	364,050

Composition of Inventories

The composition of inventories is as follows:



	September 30, 2017		December 31, 2016
	(in thousands)
Raw materials and supplies	$	19,256	$	18,893
Work in process	13,163		13,681
Finished products	74,953		63,259
Inventories	$	107,372	$	95,833

Composition of Other Current Assets

The composition of other current assets is as follows:



	September 30, 2017		December 31, 2016
	(in thousands)
Investments	$	30,351	$	3,771
Prepaid income taxes	55,416		40,705
Restricted cash	591		532
Other current assets	$	86,358	$	45,008

Composition of Other Assets

The composition of other assets is as follows:



	September 30, 2017		December 31, 2016
	(in thousands)
Life insurance policies	$	32,739	$	29,456
Venture capital investments	59,511		45,331
Restricted cash	1,944		1,736
Other	15,604		11,907
Other assets	$	109,798	$	88,430

Composition of Other Current Liabilities

The composition of other current liabilities is as follows:



	September 30, 2017		December 31, 2016
	(in thousands)
Accrued income taxes	$	32,931	$	25,621
Other	683		879
Other current liabilities	$	33,614	$	26,500

Composition of Other Long-Term Liabilities

The composition of other long-term liabilities is as follows:



	September 30, 2017		December 31, 2016
	(in thousands)
Long-term pension liability	$	91,991	$	89,984
Accrued executive supplemental life insurance retirement plan and deferred compensation plan	33,926		32,880
Other	41,576		36,375
Other long-term liabilities	$	167,493	$	159,239

Fair Value (Tables)

9 Months Ended

Sep. 30, 2017

Fair Value Disclosures [Abstract]

Summary of Assets and Liabilities Measured at Fair Value on a Recurring Basis

Assets and liabilities measured at fair value on a recurring basis are summarized below:



	September 30, 2017
	Level 1		Level 2		Level 3		Total
	(in thousands)
Cash equivalents	$	—	$	21	$	—	$	21
Other assets:
Life insurance policies	—		25,218		—		25,218
Total assets measured at fair value	$	—	$	25,239	$	—	$	25,239

Other current liabilities:
Contingent consideration	$	—	$	—	$	296	$	296
Total liabilities measured at fair value	$	—	$	—	$	296	$	296



	December 31, 2016
	Level 1		Level 2		Level 3		Total
	(in thousands)
Cash equivalents	$	—	$	21	$	—	$	21
Other assets:
Life insurance policies	—		22,121		—		22,121
Total assets measured at fair value	$	—	$	22,142	$	—	$	22,142

Other current liabilities:
Contingent consideration	$	—	$	—	$	3,621	$	3,621
Total liabilities measured at fair value	$	—	$	—	$	3,621	$	3,621

Fair Value, Contingent Consideration

The following table provides a rollforward of the contingent consideration related to the business acquisitions. See Note 2, “Business Acquisitions and Divestiture.”



	Nine Months Ended
	September 30, 2017			September 24, 2016
	(in thousands)
Beginning balance	$	3,621		$	1,370
Additions	296			3,600
Payments	(3,606		)	(874		)
Total gains or losses (realized/unrealized):
Reversal of previously recorded contingent liability and change in fair value	(15		)	30
Ending balance	$	296		$	4,126

Goodwill and Intangible Assets (Tables)

9 Months Ended

Sep. 30, 2017

Goodwill and Intangible Assets Disclosure [Abstract]

Rollforward of Goodwill

The following table provides a rollforward of the Company’s goodwill:



			Adjustments to Goodwill
	December 31, 2016		Acquisitions / (Divestitures)			Foreign Exchange		September 30, 2017
	(in thousands)
RMS	$	56,397	$	—		$	1,262	$	57,659
DSA	563,476		12,523			26,072		602,071
Manufacturing	167,644		(36,000		)	8,873		140,517
Total	$	787,517	$	(23,477	)	$	36,207	$	800,247

Schedule of Intangible Assets

The following table displays intangible assets, net by major class:



	September 30, 2017							December 31, 2016
	Gross		Accumulated Amortization			Net		Gross		Accumulated Amortization			Net
	(in thousands)
Backlog	$	8,065	$	(7,751	)	$	314	$	8,370	$	(6,390	)	$	1,980
Technology	80,256		(23,865		)	56,391		71,425		(14,314		)	57,111
Trademarks and trade names	8,617		(4,417		)	4,200		8,177		(4,124		)	4,053
Other	17,404		(7,244		)	10,160		16,775		(5,628		)	11,147
Other intangible assets	114,342		(43,277		)	71,065		104,747		(30,456		)	74,291
Client relationships	535,814		(231,432		)	304,382		519,123		(198,966		)	320,157
Intangible assets	$	650,156	$	(274,709	)	$	375,447	$	623,870	$	(229,422	)	$	394,448

Long-Term Debt and Capital Lease Obligations (Tables)

9 Months Ended

Sep. 30, 2017

Debt Disclosure [Abstract]

Schedule of Debt

Long-term debt, net consists of the following:



	September 30, 2017			December 31, 2016
	(in thousands)
Term loans	$	609,375		$	633,750
Revolving credit facility	545,373			578,759
Other long-term debt	3,675			185
Total debt	1,158,423			1,212,694
Less: current portion of long-term debt	(24,481		)	(24,560		)
Long-term debt	1,133,942			1,188,134
Debt discount and debt issuance costs	(6,233		)	(7,633		)
Long-term debt, net	$	1,127,709		$	1,180,501

Equity and Redeemable Noncontrolling Interest (Tables)

9 Months Ended

Sep. 30, 2017

Equity [Abstract]

Reconciliation of the Numerator and Denominator in the Computations of the Basic and Diluted Earnings Per Share

The following table reconciles the numerator and denominator in the computations of basic and diluted earnings per share:



	Three Months Ended					Nine Months Ended
	September 30, 2017			September 24, 2016		September 30, 2017			September 24, 2016
	(in thousands)
Numerator:
Income from continuing operations, net of income taxes	$	52,994		$	37,691	$	154,630		$	110,811
Income (loss) from discontinued operations, net of income taxes	(39		)	342		(114		)	328
Less: Net income attributable to noncontrolling interests	481			298		1,312			1,054
Net income attributable to common shareholders	$	52,474		$	37,735	$	153,204		$	110,085

Denominator:
Weighted-average shares outstanding - Basic	47,451			47,160		47,530			46,954
Effect of dilutive securities:
Stock options, restricted stock units, performance share units and restricted stock	939			874		910			884
Weighted-average shares outstanding - Diluted	48,390			48,034		48,440			47,838

Schedule of Accumulated Other Comprehensive Income

Changes to each component of accumulated other comprehensive income, net of income taxes, are as follows:



	Foreign Currency Translation Adjustment and Other			Pension and Other Post-Retirement Benefit Plans			Total
	(in thousands)
December 31, 2016	$	(154,595	)	$	(99,169	)	$	(253,764	)
Other comprehensive loss before reclassifications	68,590			—			68,590
Amounts reclassified from accumulated other comprehensive income (loss)	—			2,638			2,638
Net current period other comprehensive income	68,590			2,638			71,228
Income tax expense	—			776			776
September 30, 2017	$	(86,005	)	$	(97,307	)	$	(183,312	)

Rollforward Redeemable Noncontrolling Interest

The following table provides a rollforward of the activity related to the Company’s redeemable noncontrolling interest:



	Nine Months Ended
	September 30, 2017		September 24, 2016
	(in thousands)
Beginning balance	$	14,659	$	28,008
Purchase of 12% equity interest	—		(12,360		)
Total gains or losses (realized/unrealized):
Net income attributable to noncontrolling interest	474		462
Foreign currency translation	652		(875		)
Modification of 13% purchase option	—		1,495
Change in fair value, included in additional paid-in capital	—		(1,690		)
Ending balance	$	15,785	$	15,040

Pension and Other Post-Retirement Benefit Plans Employee Benefits (Tables)

9 Months Ended

Sep. 30, 2017

Retirement Benefits [Abstract]

Schedule of Net Periodic Cost

The following table provides the components of net periodic cost for the Company’s pension, deferred compensation and executive supplemental life insurance retirement plans:



	Three Months Ended						Nine Months Ended
	September 30, 2017			September 24, 2016			September 30, 2017			September 24, 2016
	(in thousands)
Service cost	$	749		$	655		$	2,277		$	1,848
Interest cost	2,663			2,773			8,428			9,357
Expected return on plan assets	(3,476		)	(3,038		)	(10,411		)	(11,028		)
Amortization of prior service credit	(134		)	(142		)	(392		)	(430		)
Amortization of net loss	1,017			503			3,030			1,594
Settlements	—			788			—			788
Net periodic cost	$	819		$	1,539		$	2,932		$	2,129

Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2017

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Stock-Based Compensation Expense

The following table provides stock-based compensation by the financial statement line item in which it is reflected:



	Three Months Ended						Nine Months Ended
	September 30, 2017			September 24, 2016			September 30, 2017			September 24, 2016
	(in thousands)
Cost of revenue	$	1,700		$	1,608		$	4,989		$	4,957
Selling, general and administrative	9,826			8,992			27,913			27,690
Stock-based compensation, before income taxes	11,526			10,600			32,902			32,647
Provision for income taxes	(4,099		)	(3,785		)	(11,683		)	(11,653		)
Stock-based compensation, net of income taxes	$	7,427		$	6,815		$	21,219		$	20,994

Foreign Currency Contracts (Tables)

9 Months Ended

Sep. 30, 2017

Derivative Instruments and Hedging Activities Disclosure [Abstract]

Derivative Instruments, Gain (Loss)



	Three Months Ended				Nine Months Ended
Location of Gain	September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
Other income, net	$	—	$	—	$	—	$	3,373

Restructuring and Asset Impairment (Tables)

9 Months Ended

Sep. 30, 2017

Restructuring and Related Activities [Abstract]

Rollforward of Company's Severance and Retention Costs Liability

The following table provides a rollforward of the Company’s severance and transition costs liabilities related to those initiatives:



	Three Months Ended						Nine Months Ended
	September 30, 2017			September 24, 2016			September 30, 2017			September 24, 2016
	(in thousands)
Beginning balance	$	4,004		$	3,678		$	3,680		$	2,969
Expense	690			4,015			2,900			8,135
Payments / utilization	(991		)	(2,323		)	(3,084		)	(5,676		)
Foreign currency adjustments	103			2			310			(56		)
Ending balance	$	3,806		$	5,372		$	3,806		$	5,372

Schedule of Severance and Retention Costs

The following table presents severance and transition costs by classification within the unaudited condensed consolidated statements of income:



	Three Months Ended				Nine Months Ended
	September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
Cost of services provided and products sold (excluding amortization of intangible assets)	$	240	$	3,985	$	1,717	$	4,478
Selling, general and administrative	450		30		1,183		3,657
Total severance and transition costs	$	690	$	4,015	$	2,900	$	8,135

The following presents severance and transition related costs by reportable segment:



	Three Months Ended					Nine Months Ended
	September 30, 2017			September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
RMS	$	108		$	618	$	291	$	618
DSA	135			3,367		675		7,487
Manufacturing	472			30		1,799		30
Unallocated corporate	(25		)	—		135		—
Total severance and transition costs	$	690		$	4,015	$	2,900	$	8,135

Segment Information (Tables)

9 Months Ended

Sep. 30, 2017

Segment Reporting [Abstract]

Schedule of Revenue and Other Financial Information by Business Segment

The following table presents revenue and other financial information by reportable segment:



	Three Months Ended				Nine Months Ended
	September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
RMS
Revenue	$	122,020	$	120,928	$	373,183	$	369,325
Operating income	30,726		31,224		102,016		103,055
Depreciation and amortization	5,272		5,245		15,309		15,613
Capital expenditures	6,762		2,532		13,769		5,966
DSA
Revenue	$	246,946	$	215,817	$	726,796	$	594,859
Operating income	46,616		31,303		136,966		94,514
Depreciation and amortization	20,333		20,671		58,667		51,228
Capital expenditures	10,127		4,509		25,552		13,860
Manufacturing
Revenue	$	95,266	$	88,975	$	279,145	$	250,459
Operating income	31,923		26,711		87,565		73,447
Depreciation and amortization	5,572		6,181		17,321		18,682
Capital expenditures	2,879		1,862		7,111		8,247

Reconciliation of Segment Operating Income to Consolidated Operating Income



	Operating Income						Depreciation and Amortization				Capital Expenditures
	September 30, 2017			September 24, 2016			September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
Total reportable segments	$	109,265		$	89,238		$	31,177	$	32,097	$	19,768	$	8,903
Unallocated corporate	(35,281		)	(30,443		)	2,288		2,011		2,243		665
Total consolidated	$	73,984		$	58,795		$	33,465	$	34,108	$	22,011	$	9,568



	Operating Income						Depreciation and Amortization				Capital Expenditures
	September 30, 2017			September 24, 2016			September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
Total reportable segments	$	326,547		$	271,016		$	91,297	$	85,523	$	46,432	$	28,073
Unallocated corporate	(101,781		)	(102,688		)	6,378		5,593		7,496		1,536
Total consolidated	$	224,766		$	168,328		$	97,675	$	91,116	$	53,928	$	29,609

Schedule of Net Sales for Each Significant Product or Service Offering

Revenue for each significant product or service offering is as follows:



	Three Months Ended				Nine Months Ended
	September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
RMS	$	122,020	$	120,928	$	373,183	$	369,325
DSA	246,946		215,817		726,796		594,859
Manufacturing	95,266		88,975		279,145		250,459
Total revenue	$	464,232	$	425,720	$	1,379,124	$	1,214,643

Summary of Unallocated Corporate Overhead

A summary of unallocated corporate expense consists of the following:



	Three Months Ended				Nine Months Ended
	September 30, 2017		September 24, 2016		September 30, 2017		September 24, 2016
	(in thousands)
Stock-based compensation	$	7,255	$	6,739	$	20,259	$	20,593
Compensation, benefits, and other employee-related expenses	11,771		9,048		37,812		29,327
External consulting and other service expenses	6,729		4,545		16,581		16,377
Information technology	3,237		2,903		9,247		8,399
Depreciation	2,287		2,011		6,378		5,593
Acquisition and integration	1,327		2,033		2,539		13,056
Other general unallocated corporate	2,675		3,164		8,965		9,343
Total unallocated corporate expense	$	35,281	$	30,443	$	101,781	$	102,688

Basis of Presentation (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
Basis of Presentation (Details) - USD ($) $ in Thousands	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016	Dec. 31, 2016	Dec. 26, 2015
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Restricted cash combined with unrestricted cash	$ 126,153	$ 108,119	$ 126,153	$ 108,119	$ 119,894	$ 119,963
Reclassification of net cash provided by operating activities			193,838	198,252
Cash reclassified from investing activities			39,759	617,669
Impact to income statement from recognition of excess tax benefits and tax deficiencies	$ 900		9,700
Reclassification of net cash provided by financing activities			$ 155,466	(404,682)
Accounting Standards Update 2016-09
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Reclassification of net cash provided by operating activities				9,500
Reclassification of net cash provided by financing activities		9,100
New Accounting Pronouncement, Early Adoption, Effect \| Accounting Standards Update 2016-18
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Restricted cash combined with unrestricted cash		$ 2,400		2,400		$ 2,000
New Accounting Pronouncement, Early Adoption, Effect \| Accounting Standards Update 2016-15
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Reclassification of net cash provided by operating activities				2,200
Cash reclassified from investing activities				$ 2,200

Business Acquisitions and Divestiture - Brains On-Line Additional Information (Details) - Brains On-Line $ in Thousands, € in Millions		3 Months Ended	9 Months Ended
	Aug. 04, 2017 USD ($)	Sep. 30, 2017 USD ($)	Sep. 30, 2017 USD ($)	Aug. 04, 2017 EUR (€)	Aug. 04, 2017 USD ($)
Business Acquisition [Line Items]
Purchase price	$ 21,300
Undiscounted contingent payments				€ 6.7	$ 7,900
Purchase price allocation					$ 20,646
Cash acquired	$ 700
Integration related costs and transaction costs		$ 1,200	$ 2,100

Business Acquisitions and Divestiture - Brains On-Line Purchase Price Allocation (Details) - USD ($) $ in Thousands	Sep. 30, 2017	Aug. 04, 2017	Dec. 31, 2016
Business Acquisition [Line Items]
Goodwill	$ 800,247		$ 787,517
Brains On-Line
Business Acquisition [Line Items]
Trade receivables, contractual amount		$ 1,146
Trade receivables		1,146
Other current assets (excluding cash)		670
Property, plant and equipment		664
Other long-term assets		13
Definite-lived intangible assets		9,300
Goodwill		12,324
Other current liabilities		(863)
Deferred revenue		(405)
Long-term liabilities		(2,203)
Total purchase price allocation		$ 20,646

Business Acquisitions and Divestiture - Brains On-Line Definite-Lived Intangible Assets (Details) - Brains On-Line $ in Thousands	Aug. 04, 2017 USD ($)
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 9,300
Weighted Average Amortization Life	12 years
Client relationships
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 7,000
Weighted Average Amortization Life	13 years
Other intangible assets
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 2,300
Weighted Average Amortization Life	10 years

Business Acquisitions and Divestiture - Agilux Additional Information (Details) - Agilux Laboratories - USD ($) $ in Thousands		3 Months Ended		9 Months Ended
	Sep. 28, 2016	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Business Acquisition [Line Items]
Purchase price	$ 64,900
Purchase price allocation	62,025
Cash acquired	$ 2,900
Integration related costs and transaction costs		$ 0	$ 1,100	$ 300	$ 1,100

Business Acquisitions and Divestiture - Agilux Purchase Price Allocation (Details) - USD ($) $ in Thousands	Sep. 30, 2017	Dec. 31, 2016	Sep. 28, 2016
Business Acquisition [Line Items]
Goodwill	$ 800,247	$ 787,517
Agilux Laboratories
Business Acquisition [Line Items]
Trade receivables, contractual amount			$ 4,799
Trade receivables			4,799
Other current assets (excluding cash)			794
Property, plant and equipment			3,907
Other long-term assets			11
Definite-lived intangible assets			21,900
Goodwill			44,517
Other current liabilities			(3,812)
Long-term liabilities			(10,091)
Total purchase price allocation			$ 62,025

Business Acquisitions and Divestiture - Agilux Definite-Lived Intangible Assets (Details) - Agilux Laboratories $ in Thousands	Sep. 28, 2016 USD ($)
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 21,900
Weighted Average Amortization Life	14 years
Client relationships
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 16,700
Weighted Average Amortization Life	17 years
Other intangible assets
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 5,200
Weighted Average Amortization Life	4 years

Business Acquisitions and Divestiture - Blue Stream Additional Information (Details) - Blue Stream Laboratories - USD ($) $ in Thousands		3 Months Ended	9 Months Ended
	Jun. 27, 2016	Sep. 30, 2017	Sep. 30, 2017	Sep. 24, 2016
Business Acquisition [Line Items]
Purchase price	$ 11,700
Cash acquired	0
Maximum contingent consideration	3,000
Purchase price allocation	$ 11,749
Integration related costs and transaction costs		$ 0	$ 0	$ 400

Business Acquisitions and Divestiture - Blue Stream Purchase Price Allocation (Details) - USD ($) $ in Thousands	Sep. 30, 2017	Dec. 31, 2016	Jun. 27, 2016
Business Acquisition [Line Items]
Goodwill	$ 800,247	$ 787,517
Blue Stream Laboratories
Business Acquisition [Line Items]
Trade receivables, contractual amount			$ 1,104
Trade receivables			1,104
Other current assets (excluding cash)			15
Property, plant and equipment			912
Other long-term assets			187
Definite-lived intangible assets			1,230
Goodwill			10,334
Current liabilities			(1,132)
Long-term liabilities			(901)
Total purchase price allocation			$ 11,749

Business Acquisitions and Divestiture - Blue Stream Definite Lived Intangible Assets (Details) - Blue Stream Laboratories $ in Thousands	Jun. 27, 2016 USD ($)
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 1,230
Weighted Average Amortization Life	7 years
Client relationships
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 650
Weighted Average Amortization Life	10 years
Other intangible assets
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 580
Weighted Average Amortization Life	5 years

Business Acquisitions and Divestiture - WIL Research Additional Information (Details) - USD ($)		3 Months Ended		9 Months Ended
	Apr. 04, 2016	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016	Feb. 11, 2017	Feb. 10, 2017	Mar. 30, 2016
Business Acquisition [Line Items]
Credit facility								$ 1,650,000,000.00
WIL Research
Business Acquisition [Line Items]
Purchase price	$ 604,800,000
Assumed liabilities	400,000
Purchase price allocation	577,391,000
Cash acquired	$ 27,400,000
Goodwill, expected tax deductible amount						$ 14,800,000	$ 19,000,000
Integration related costs and transaction costs		$ 400,000	$ 1,300,000	$ 1,600,000	$ 13,700,000
Revenue			57,400,000		112,600,000
Operating income			$ 3,600,000		4,600,000
Amortization of intangible assets and depreciation of fixed assets					1,400,000
Reversal of interest expense on borrowings					$ 2,700,000

Business Acquisitions and Divestiture - WIL Research Purchase Price Allocation (Details) - USD ($) $ in Thousands	Sep. 30, 2017	Dec. 31, 2016	Apr. 04, 2016
Business Acquisition [Line Items]
Goodwill	$ 800,247	$ 787,517
WIL Research
Business Acquisition [Line Items]
Trade receivables, contractual amount			$ 48,625
Trade receivables			48,157
Inventories			2,296
Other current assets (excluding cash)			3,814
Property, plant and equipment			129,066
Other long-term assets			1,060
Definite-lived intangible assets			164,800
Goodwill			330,175
Deferred revenue			(39,103)
Other current liabilities			(27,386)
Long-term liabilities			(35,488)
Total purchase price allocation			$ 577,391

Business Acquisitions and Divestiture - WIL Research Definite Lived Intangible Assets (Details) - WIL Research $ in Thousands	Apr. 04, 2016 USD ($)
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 164,800
Weighted Average Amortization Life	13 years
Client relationships
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 137,500
Weighted Average Amortization Life	15 years
Developed technology
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 20,700
Weighted Average Amortization Life	3 years
Backlog
Business Acquisition [Line Items]
Definite-Lived Intangible Assets	$ 6,600
Weighted Average Amortization Life	1 year

Business Acquisitions and Divestiture - WIL Laboratories, Pro Forma Financial Information (Details) - WIL Research - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended	9 Months Ended
	Sep. 24, 2016	Sep. 24, 2016
Business Acquisition [Line Items]
Revenue	$ 425,720	$ 1,275,175
Net income attributable to common shareholders	$ 39,530	$ 129,050
Earnings per common share
Basic (in dollars per share)	$ 0.84	$ 2.75
Diluted (in dollars per share)	$ 0.82	$ 2.70

Business Acquisitions and Divestiture - Contract Manufacturing, Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
	Apr. 01, 2017	Sep. 30, 2017	Sep. 24, 2016	Feb. 10, 2017
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Gain on divestiture		$ 10,577	$ 0
Disposal Group, Disposed of by Sale, Not Discontinued Operations \| CDMO Business
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Cash received from divestiture				$ 75,000
Cash and cash equivalents transferred				600
Working capital adjustments				$ 300
Gain on divestiture	$ 10,600

Business Acquisitions and Divestiture - Contract Manufacturing, Schedule of Assets and Liabilities Disposed (Details) - USD ($) $ in Thousands	Sep. 30, 2017	Feb. 10, 2017	Dec. 31, 2016
Liabilities
Deferred revenue	$ 1,650		$ 1,623
Other current liabilities	$ 4,395		$ 5,771
CDMO Business \| Disposal Group, Disposed of by Sale, Not Discontinued Operations
Assets
Current assets		$ 5,505
Property, plant and equipment, net		11,174
Goodwill		35,857
Long-term assets		17,154
Total assets		69,690
Liabilities
Deferred revenue		4,878
Other current liabilities		1,158
Total liabilities		$ 6,036

Supplemental Balance Sheet Information (Details) - USD ($) $ in Thousands	Sep. 30, 2017	Dec. 31, 2016	Sep. 24, 2016
Composition of trade receivables
Client receivables	$ 321,472	$ 283,997
Unbilled revenue	103,389	82,203
Total	424,861	366,200
Less: Allowance for doubtful accounts	(2,526)	(2,150)
Trade receivables, net	422,335	364,050
Composition of inventories
Raw materials and supplies	19,256	18,893
Work in process	13,163	13,681
Finished products	74,953	63,259
Inventories	107,372	95,833
Composition of other current assets
Investments	30,351	3,771
Prepaid income taxes	55,416	40,705
Restricted cash	591	532	$ 572
Other current assets	86,358	45,008
Composition of other assets
Life insurance policies	32,739	29,456
Venture capital investments	59,511	45,331
Restricted cash	1,944	1,736	$ 1,825
Other	15,604	11,907
Other assets	109,798	88,430
Composition of other current liabilities
Accrued income taxes	32,931	25,621
Other	683	879
Other current liabilities	33,614	26,500
Composition of other long-term liabilities
Long-term pension liability	91,991	89,984
Accrued executive supplemental life insurance retirement plan and deferred compensation plan	33,926	32,880
Other	41,576	36,375
Other long-term liabilities	$ 167,493	$ 159,239

Venture Capital Investments and Marketable Securities - Additional Information (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Schedule of Equity Method Investments [Line Items]
Committed contribution	$ 87.7		$ 87.7
Venture capital investments	48.0		48.0
Dividends received	3.3	$ 2.3	7.7	$ 2.3
Gain (loss) from venture capital investments	$ 5.8	$ 0.4	$ 12.5	$ 8.5
Minimum
Schedule of Equity Method Investments [Line Items]
Ownership percentage	0.70%		0.70%
Maximum
Schedule of Equity Method Investments [Line Items]
Ownership percentage	12.10%		12.10%

Fair Value - Fair Value of Assets and Liabilities (Details) - USD ($) $ in Thousands	Sep. 30, 2017	Dec. 31, 2016
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash equivalents	$ 21	$ 21
Other assets:
Life insurance policies	25,218	22,121
Total assets measured at fair value	25,239	22,142
Other current liabilities:
Contingent consideration	296	3,621
Total liabilities measured at fair value	296	3,621
Level 1
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash equivalents	0	0
Other assets:
Life insurance policies	0	0
Total assets measured at fair value	0	0
Other current liabilities:
Contingent consideration	0	0
Total liabilities measured at fair value	0	0
Level 2
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash equivalents	21	21
Other assets:
Life insurance policies	25,218	22,121
Total assets measured at fair value	25,239	22,142
Other current liabilities:
Contingent consideration	0	0
Total liabilities measured at fair value	0	0
Level 3
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash equivalents	0	0
Other assets:
Life insurance policies	0	0
Total assets measured at fair value	0	0
Other current liabilities:
Contingent consideration	296	3,621
Total liabilities measured at fair value	$ 296	$ 3,621

Fair Value - Contingent Consideration (Details) - Contingent Consideration - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Beginning balance	$ 3,621	$ 1,370
Additions	296	3,600
Payments	(3,606)	(874)
Total gains or losses (realized/unrealized):
Reversal of previously recorded contingent liability and change in fair value	(15)	30
Ending balance	$ 296	$ 4,126

Goodwill and Intangible Assets - Gross Carrying Amount and Accumulated Amortization of Goodwill (Details) $ in Thousands	9 Months Ended
	Sep. 30, 2017 USD ($)
Changes in gross carrying amount and accumulated amortization of goodwill
December 31, 2016	$ 787,517
Acquisitions / (Divestitures)	(23,477)
Foreign Exchange	36,207
September 30, 2017	800,247
RMS
Changes in gross carrying amount and accumulated amortization of goodwill
December 31, 2016	56,397
Acquisitions / (Divestitures)	0
Foreign Exchange	1,262
September 30, 2017	57,659
DSA
Changes in gross carrying amount and accumulated amortization of goodwill
December 31, 2016	563,476
Acquisitions / (Divestitures)	(12,523)
Foreign Exchange	26,072
September 30, 2017	602,071
Manufacturing
Changes in gross carrying amount and accumulated amortization of goodwill
December 31, 2016	167,644
Acquisitions / (Divestitures)	(36,000)
Foreign Exchange	8,873
September 30, 2017	$ 140,517

Goodwill and Intangible Assets - Schedule of Other Intangible Assets (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 26, 2016	Sep. 30, 2017	Dec. 31, 2016
Other intangible assets
Gross		$ 650,156	$ 623,870
Accumulated Amortization		(274,709)	(229,422)
Net		375,447	394,448
Impairment charge	$ 1,900
Backlog
Other intangible assets
Gross		8,065	8,370
Accumulated Amortization		(7,751)	(6,390)
Net		314	1,980
Backlog \| CDMO Business \| Disposal Group, Disposed of by Sale, Not Discontinued Operations
Other intangible assets
Decrease in intangible assets resulting from divestiture of business		300
Technology
Other intangible assets
Gross		80,256	71,425
Accumulated Amortization		(23,865)	(14,314)
Net		56,391	57,111
Trademarks and trade names
Other intangible assets
Gross		8,617	8,177
Accumulated Amortization		(4,417)	(4,124)
Net		4,200	4,053
Other
Other intangible assets
Gross		17,404	16,775
Accumulated Amortization		(7,244)	(5,628)
Net		10,160	11,147
Other intangible assets
Other intangible assets
Gross		114,342	104,747
Accumulated Amortization		(43,277)	(30,456)
Net		71,065	74,291
Client relationships
Other intangible assets
Gross		535,814	519,123
Accumulated Amortization		(231,432)	(198,966)
Net		304,382	$ 320,157
Client relationships \| CDMO Business \| Disposal Group, Disposed of by Sale, Not Discontinued Operations
Other intangible assets
Decrease in intangible assets resulting from divestiture of business		$ 16,800

Long-Term Debt and Capital Lease Obligations - Schedule of Long-Term Debt (Details) - USD ($) $ in Thousands	Sep. 30, 2017	Dec. 31, 2016
Debt Instrument [Line Items]
Total debt	$ 1,158,423	$ 1,212,694
Less: current portion of long-term debt	(24,481)	(24,560)
Long-term debt	1,133,942	1,188,134
Debt discount and debt issuance costs	(6,233)	(7,633)
Long-term debt, net	1,127,709	1,180,501
Term loans
Debt Instrument [Line Items]
Total debt	609,375	633,750
Revolving credit facility
Debt Instrument [Line Items]
Total debt	545,373	578,759
Other long-term debt
Debt Instrument [Line Items]
Total debt	$ 3,675	$ 185

Long-Term Debt and Capital Lease Obligations - Additional Information (Details)		9 Months Ended
	Mar. 30, 2016 USD ($) payment	Sep. 30, 2017 USD ($)	Sep. 24, 2016 USD ($)	Dec. 31, 2016 USD ($)
Debt Instrument [Line Items]
Weighted average interest rate		2.26%		1.89%
Credit facility	$ 1,650,000,000.00
Expensed debt issuance costs			$ 1,000,000
Maximum borrowing capacity, term loan and line of credit facility, potential increase available	$ 500,000,000
Number of consecutive fiscal periods		1 year
Credit facility
Debt Instrument [Line Items]
Minimum EBITDA less capital expenditures to consolidated cash interest expense ratio	3.50
Maximum consolidated indebtedness to consolidated EBITDA	3.75
Maximum consolidated indebtedness to consolidated EBITDA, with step-downs	3.50
Other Capital Lease Obligations
Debt Instrument [Line Items]
Other capital lease obligations		$ 30,900,000		$ 29,900,000
Letter of Credit
Debt Instrument [Line Items]
Letters of credit outstanding		$ 4,900,000		$ 4,900,000
Federal Funds Rate
Debt Instrument [Line Items]
Interest rate	0.50%
LIBOR
Debt Instrument [Line Items]
Interest rate	1.00%
Term Loan Facility
Debt Instrument [Line Items]
Credit facility	$ 650,000,000.0
Number of quarterly installment payments \| payment	19
Multi-currency Revolving Facility
Debt Instrument [Line Items]
Credit facility	$ 1,000,000,000.0

Equity and Redeemable Noncontrolling Interest - Earnings Per Share (Details) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Numerator:
Income from continuing operations, net of income taxes	$ 52,994	$ 37,691	$ 154,630	$ 110,811
Income (loss) from discontinued operations, net of income taxes	(39)	342	(114)	328
Less: Net income attributable to noncontrolling interests	481	298	1,312	1,054
Net income attributable to common shareholders	$ 52,474	$ 37,735	$ 153,204	$ 110,085
Denominator:
Weighted-average shares outstanding—Basic (in shares)	47,451	47,160	47,530	46,954
Effect of dilutive securities:
Stock options, restricted stock units, performance share units and restricted stock (in shares)	939	874	910	884
Weighted-average shares outstanding—Diluted (in shares)	48,390	48,034	48,440	47,838

Equity and Redeemable Noncontrolling Interest - Earnings Per Share, Additional Information (Details) - shares shares in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Employee Stock Option
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive securities excluded from computation of earnings per share amount (in shares)	0.4	0.6	0.6	0.9
Restricted Stock and Restricted Stock Units
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive securities excluded from computation of earnings per share amount (in shares)			1.1	1.1

Equity and Redeemable Noncontrolling Interest - Treasury Shares (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	May 09, 2017
Treasury Shares
Purchase of treasury stock	$ 106,902	$ 12,226
Shares acquired to satisfy minimum individual statutory tax withholdings for vesting of equity instruments (in shares)	200,000	200,000
Shares acquired to satisfy minimum individual statutory tax withholdings for vesting of equity instruments	$ 16,300	$ 12,200
Authorized Share Repurchase Program
Treasury Shares
Stock repurchased during period (in shares)	1,000,000	0
Purchase of treasury stock	$ 90,600
Stock repurchase authorization			$ 150,000
Aggregate amount authorized			$ 1,300,000
Remaining authorized repurchase amount	$ 129,100

Equity and Redeemable Noncontrolling Interest - Accumulated Other Comprehensive Income (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Accumulated Other Comprehensive Income (Loss), before Tax [Roll Forward]
Other comprehensive loss before reclassifications			$ 68,590
Amounts reclassified from accumulated other comprehensive income (loss)			2,638
Net current period other comprehensive income			71,228
Income tax expense	$ 153	$ 140	776	$ 424
Foreign Currency Translation Adjustment and Other
Accumulated Other Comprehensive Income (Loss), before Tax [Roll Forward]
December 31, 2016			(154,595)
Other comprehensive loss before reclassifications			68,590
Amounts reclassified from accumulated other comprehensive income (loss)			0
Net current period other comprehensive income			68,590
Income tax expense			0
September 30, 2017	(86,005)		(86,005)
Pension and Other Post-Retirement Benefit Plans
Accumulated Other Comprehensive Income (Loss), before Tax [Roll Forward]
December 31, 2016			(99,169)
Other comprehensive loss before reclassifications			0
Amounts reclassified from accumulated other comprehensive income (loss)			2,638
Net current period other comprehensive income			2,638
Income tax expense	200	$ 100	776	$ 400
September 30, 2017	(97,307)		(97,307)
Total
Accumulated Other Comprehensive Income (Loss), before Tax [Roll Forward]
December 31, 2016			(253,764)
September 30, 2017	$ (183,312)		$ (183,312)

Equity and Redeemable Noncontrolling Interest Equity and Redeemable Noncontrolling Interest - Nonredeemable Noncontrolling Interest, Additional Information (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Equity [Abstract]
Nonredeemable Noncontrolling Interest Activity	$ 0.3	$ 0.1	$ 0.8	$ 0.4

Equity and Redeemable Noncontrolling Interest - Redeemable Noncontrolling Interest, Additional Information (Details) - USD ($) $ in Millions	Sep. 30, 2017	Jul. 07, 2016	Jan. 31, 2013
Investment [Line Items]
Contractually defined redemption value	$ 15.0
Vital River
Investment [Line Items]
Ownership percentage	87.00%	12.00%	75.00%
Noncontrolling interest ownership percentage	13.00%

Equity and Redeemable Noncontrolling Interest - Rollforward of Redeemable Noncontrolling Interest (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016
Increase (Decrease) in Temporary Equity [Roll Forward]
Beginning balance	$ 14,659	$ 28,008
Noncontrolling Interest, Decrease from Redemptions or Purchase of Interests	0	(12,360)
Total gains or losses (realized/unrealized):
Income (loss) attributable to noncontrolling interest	0	1,495
Foreign currency translation	652	(875)
Ending balance	15,785	15,040
Net income attributable to noncontrolling interest
Total gains or losses (realized/unrealized):
Income (loss) attributable to noncontrolling interest	474	462
Change in fair value, included in additional paid-in capital
Total gains or losses (realized/unrealized):
Income (loss) attributable to noncontrolling interest	$ 0	$ (1,690)

Income Taxes (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
Income Taxes (Details) - USD ($) $ in Thousands	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Effective tax rate	27.30%	29.20%	32.20%	30.40%
Effective Income Tax Rate Reconciliation, Settlement Proceedings, Excess Tax Benefit, Amount	$ 1,200
Tax benefit associated with stock compensation	900		$ 9,700
Decrease in unrecognized tax benefits	800
Unrecognized tax benefits	25,200		25,200
Increase in unrecognized tax benefits that would impact effective tax rate			300
Unrecognized tax benefits that would impact effective tax rate	23,200		23,200
Accrued interest and penalties on unrecognized tax benefits	2,600		2,600
Decrease in unrecognized tax benefits that are reasonably possibly over the next twelve-month period	900		900
Income tax expense	153	$ 140	776	$ 424
Pension and Other Post-Retirement Benefit Plans
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Income tax expense	$ 200	$ 100	776	$ 400
CDMO Business \| Disposal Group, Disposed of by Sale, Not Discontinued Operations
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Tax on gain on divestiture			$ 18,000

Pension and Other Post-Retirement Benefit Plans (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Pension
Employee benefits
Service cost	$ 749	$ 655	$ 2,277	$ 1,848
Interest cost	2,663	2,773	8,428	9,357
Expected return on plan assets	(3,476)	(3,038)	(10,411)	(11,028)
Amortization of prior service credit	(134)	(142)	(392)	(430)
Amortization of net loss	1,017	503	3,030	1,594
Settlements	0	788	0	788
Net periodic cost	819	1,539	2,932	2,129
Post-retirement Benefit Plan
Employee benefits
Net periodic cost	$ 0	$ 0	$ 0	$ 0

Stock-Based Compensation - Stock Based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Stock-based compensation expense
Stock-based compensation, before income taxes	$ 11,526	$ 10,600	$ 32,902	$ 32,647
Provision for income taxes	(4,099)	(3,785)	(11,683)	(11,653)
Stock-based compensation, net of income taxes	7,427	6,815	21,219	20,994
Cost of revenue
Stock-based compensation expense
Stock-based compensation, before income taxes	1,700	1,608	4,989	4,957
Selling, general and administrative
Stock-based compensation expense
Stock-based compensation, before income taxes	$ 9,826	$ 8,992	$ 27,913	$ 27,690

Stock-Based Compensation - Summary of Stock-Based Compensation Grants (Details) shares in Millions	9 Months Ended
	Sep. 30, 2017 $ / shares shares
Stock Options
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock options granted (in shares)	0.6
Stock options weighted average grant date fair value (in dollars per share) \| $ / shares	$ 18.30
Restricted Stock Units
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares granted (in shares)	0.2
Weighted-average grant date fair value (in dollars per share) \| $ / shares	$ 88.52
Performance Stock Units
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares granted (in shares)	0.2
Weighted-average grant date fair value (in dollars per share) \| $ / shares	$ 99.24
Maximum shares to be awarded under plan (in shares)	0.4

Foreign Currency Contracts - Effect on Statement of Income (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Other income (expense), net \| Foreign Currency Forward Contract
Derivatives, Fair Value [Line Items]
Gain (loss) recognized	$ 0	$ 0	$ 0	$ 3,373

Commitments and Contingencies (Details) $ in Millions	9 Months Ended
Commitments and Contingencies (Details) $ in Millions	Sep. 30, 2017 USD ($)
Commitments and Contingencies Disclosure [Abstract]
Increase in lease obligations	$ 37.9

Restructuring and Asset Impairment - Rollforward of Severance and Retention Costs Liability (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Restructuring Reserve [Roll Forward]
Beginning balance	$ 4,004	$ 3,678	$ 3,680	$ 2,969
Expense	690	4,015	2,900	8,135
Payments / utilization	(991)	(2,323)	(3,084)	(5,676)
Foreign currency adjustments	103	2	310	(56)
Ending balance	$ 3,806	$ 5,372	$ 3,806	$ 5,372

Restructuring and Asset Impairment - Narrative (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended		15 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016	Dec. 31, 2018	Nov. 08, 2017	Jul. 01, 2017	Dec. 31, 2016	Jun. 25, 2016	Dec. 26, 2015
Restructuring Cost and Reserve [Line Items]
Severance and retention costs liability	$ 3,806	$ 5,372	$ 3,806	$ 5,372			$ 4,004	$ 3,680	$ 3,678	$ 2,969
Impairment charges	100	4,300	300	4,300
Accelerated depreciation	100	100	200	500
Other restructuring costs		$ 800	400	$ 800
Accrued Compensation
Restructuring Cost and Reserve [Line Items]
Severance and retention costs liability	$ 3,400		$ 3,400
Subsequent Event \| RMS \| Minimum
Restructuring Cost and Reserve [Line Items]
Expected restructuring costs						$ 18,000
Subsequent Event \| RMS \| Maximum
Restructuring Cost and Reserve [Line Items]
Expected restructuring costs						$ 24,000
Subsequent Event \| RMS \| Scenario, Forecast
Restructuring Cost and Reserve [Line Items]
Impairment charges					$ 17,000
Accelerated lease obligations					5,000
Payments for restructuring					$ 6,000

Restructuring and Asset Impairment - Severance and Retention Costs by Classification on the Consolidated Statements of Income (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Restructuring Cost and Reserve [Line Items]
Total severance and transition costs	$ 690	$ 4,015	$ 2,900	$ 8,135
Cost of services provided and products sold (excluding amortization of intangible assets)
Restructuring Cost and Reserve [Line Items]
Total severance and transition costs	240	3,985	1,717	4,478
Selling, general and administrative
Restructuring Cost and Reserve [Line Items]
Total severance and transition costs	$ 450	$ 30	$ 1,183	$ 3,657

Restructuring and Asset Impairment - Severance and Retention Costs by Reportable Segment (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Segment Reporting Information [Line Items]
Total severance and transition costs	$ 690	$ 4,015	$ 2,900	$ 8,135
RMS
Segment Reporting Information [Line Items]
Total severance and transition costs	108	618	291	618
DSA
Segment Reporting Information [Line Items]
Total severance and transition costs	135	3,367	675	7,487
Manufacturing
Segment Reporting Information [Line Items]
Total severance and transition costs	472	30	1,799	30
Unallocated corporate
Segment Reporting Information [Line Items]
Total severance and transition costs	$ (25)	$ 0	$ 135	$ 0

Segment Information - Narrative (Details)	9 Months Ended
Segment Information - Narrative (Details)	Sep. 30, 2017 segments
Segment Reporting [Abstract]
Number of reportable segments	3

Segment Information - Revenue and Other Financial Information by Reportable Segment (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Segment Reporting Information [Line Items]
Revenue	$ 464,232	$ 425,720	$ 1,379,124	$ 1,214,643
Operating income	73,984	58,795	224,766	168,328
Depreciation and amortization	33,465	34,108	97,675	91,116
Capital expenditures	22,011	9,568	53,928	29,609
Operating segments
Segment Reporting Information [Line Items]
Operating income	109,265	89,238	326,547	271,016
Depreciation and amortization	31,177	32,097	91,297	85,523
Capital expenditures	19,768	8,903	46,432	28,073
RMS \| Operating segments
Segment Reporting Information [Line Items]
Revenue	122,020	120,928	373,183	369,325
Operating income	30,726	31,224	102,016	103,055
Depreciation and amortization	5,272	5,245	15,309	15,613
Capital expenditures	6,762	2,532	13,769	5,966
DSA \| Operating segments
Segment Reporting Information [Line Items]
Revenue	246,946	215,817	726,796	594,859
Operating income	46,616	31,303	136,966	94,514
Depreciation and amortization	20,333	20,671	58,667	51,228
Capital expenditures	10,127	4,509	25,552	13,860
Manufacturing \| Operating segments
Segment Reporting Information [Line Items]
Revenue	95,266	88,975	279,145	250,459
Operating income	31,923	26,711	87,565	73,447
Depreciation and amortization	5,572	6,181	17,321	18,682
Capital expenditures	$ 2,879	$ 1,862	$ 7,111	$ 8,247

Segment Information - Reconciliation of Segment Operating Income, Depreciation and Amortization, and Capital Expenditures (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Segment Reporting Information [Line Items]
Operating income	$ 73,984	$ 58,795	$ 224,766	$ 168,328
Depreciation and amortization	33,465	34,108	97,675	91,116
Capital expenditures	22,011	9,568	53,928	29,609
Total reportable segments
Segment Reporting Information [Line Items]
Operating income	109,265	89,238	326,547	271,016
Depreciation and amortization	31,177	32,097	91,297	85,523
Capital expenditures	19,768	8,903	46,432	28,073
Unallocated corporate
Segment Reporting Information [Line Items]
Operating income	(35,281)	(30,443)	(101,781)	(102,688)
Depreciation and amortization	2,288	2,011	6,378	5,593
Capital expenditures	$ 2,243	$ 665	$ 7,496	$ 1,536

Segment Information - Revenue Per Significant Product or Service (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Segment Reporting Information [Line Items]
Revenue	$ 464,232	$ 425,720	$ 1,379,124	$ 1,214,643
Operating segments \| RMS
Segment Reporting Information [Line Items]
Revenue	122,020	120,928	373,183	369,325
Operating segments \| DSA
Segment Reporting Information [Line Items]
Revenue	246,946	215,817	726,796	594,859
Operating segments \| Manufacturing
Segment Reporting Information [Line Items]
Revenue	$ 95,266	$ 88,975	$ 279,145	$ 250,459

Segment Information - Summary of Unallocated Corporate Overhead (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 24, 2016	Sep. 30, 2017	Sep. 24, 2016
Segment Reporting Information [Line Items]
Stock-based compensation	$ 11,526	$ 10,600	$ 32,902	$ 32,647
Unallocated corporate
Segment Reporting Information [Line Items]
Stock-based compensation	7,255	6,739	20,259	20,593
Compensation, benefits, and other employee-related expenses	11,771	9,048	37,812	29,327
External consulting and other service expenses	6,729	4,545	16,581	16,377
Information technology	3,237	2,903	9,247	8,399
Depreciation	2,287	2,011	6,378	5,593
Acquisition and integration	1,327	2,033	2,539	13,056
Other general unallocated corporate	2,675	3,164	8,965	9,343
Total unallocated corporate expense	$ 35,281	$ 30,443	$ 101,781	$ 102,688